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Biotech / Medical : momo-T/FIF -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (11744)10/15/2018 7:33:41 PM
From: scaram(o)uche  Read Replies (1) | Respond to of 12215
 
Volume dries up with overhang intact. Oh joy.

They say that the death and life threatening events occurred in the last cohorts of each trial. I'm taking that at face value and assuming that it means "by design". Sure would be helpful to know if the actual dose was the same for each of the "last" cohorts. Anybody gotten that far or know how to find the doses? Have not yet looked through old posters.

edit: when the neuro issue hit car-t at its hardest, many were saying that bispecifics would be fine tuned to have the efficacy, but that toxicities could be more readily controlled. But when you hit a hard and fast wall like that which may have been hit in the combo of these two trials? Might be good to drop down and expand more than one cohort before moving on to phase II?



To: scaram(o)uche who wrote (11744)10/26/2018 3:31:00 PM
From: scaram(o)uche  Respond to of 12215
 
330K block, a pittance. But at least it has started.