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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID -- Ignore unavailable to you. Want to Upgrade?

To: Maurice Winn who wrote (1441)	1/19/1998 12:07:00 AM
From: Scott	Read Replies (1) \| Respond to of 1762

Maurice, I'm sure that many readers of this thread will have you, your son, and your family in our thoughts and prayers. I hope some of the readers who have expertise in the matter of obtaining drug for offlabel use, and getting reimbursement, will share their expertise. I will certainly be tapping into my network for ideas. One suggestion: If you have not already done this, try giving Idec's customer service and investor relations people a call. And drop a line to the president, Bill Rastetter. The whole company is made up of very decent people, who appear to really care about meeting the medical needs of their patient constituencies, and I would bet that you would get some inside people who would try to help you find a way to get your son Rituxan, if that is appropriate for his specific NHL. Please let us know what happens, both with your son and with Idec's responsiveness. - Scott (about to go kiss my 2 sleeping little ones and count my blessings.)

To: Maurice Winn who wrote (1441)	1/21/1998 2:30:00 AM
From: DMB	1 Recommendation Respond to of 1762

Maurice, I am sorry to hear about your son. I hope he is doing OK. Here in the US, now that the FDA has approved Rituxan physicians, are free to use the drug for off label purposes (as far as the FDa is concerned). Of course, there are many other considerations including reimbursement, malpractice liability, "community standards", and not least of all, good judgement. DMB

To: Maurice Winn who wrote (1441)	12/9/2007 10:44:24 AM
From: Maurice Winn	Respond to of 1762

You were right all along Mq: rituxan.com 5 year survival zooms up with Rituxan. We can now calculate how many people died because of the delays. It was a LOT. People go on and on about 911 as though it was a problem. More people have died because of FDA/Medical Guild "due process" and stupidity than from Osama's gang on 911. <Rituxan plus CHOP chemotherapy is the most common treatment for DLBCL. Known as R-CHOP, this combination can significantly improve treatment results when compared with CHOP chemotherapy alone as an initial treatment for DLBCL. In a large clinical study, Rituxan plus CHOP chemotherapy was shown to significantly prolong survival in patients followed for up to 5 years.? At 2 years, 69% of patients receiving Rituxan plus CHOP chemotherapy were surviving versus 58% of those receiving CHOP chemotherapy alone. At 5 years, 58% of patients who received Rituxan plus CHOP chemotherapy were surviving versus 46% of those who received CHOP chemotherapy alone. > So, for every 100 treated with one or the other, another 12 would have lived if they had had the Rituxan too. That is a huge improvement over the 46 who lived with CHOP alone. It makes me sick to think of it. It's criminal! A total layman could figure it out with a few weeks of studying. With some 50,000 new cases a year of various lymphomas, that's a LOT of people who died for "due process" and bureaucratic inertia and central government and Medical Guild control. Well done chaps! Without getting the actual market share of Diffuse large B Cell NHL I think it's about 20,000 per year so that's about 2,000 a year people dead for lack of the right treatment. [Just in the USA] That's like one 911 attack a year - but it gets zero publicity yet 911 gets news around the clock and has wars fought and umpty mega$billions spent on taking shoes off at airports and confiscating toothpaste from children. Way to go guys! Mqurice