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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?

To: Tunica Albuginea who wrote (4779)	1/19/1998 4:43:00 PM
From: BigKNY3	Read Replies (2) \| Respond to of 23519

TA : Thanks for reviewing my response. Please provide your reference sources . Quite frankly, it is difficult to believe someone who does not know the difference between a specific PDE-V inhibitor and a specific PDE-III inhibitor. Next thing you know , you will be comparing the pharmacokinetics of Viagra to the SSRI Redux. ...Oops, you already have. BigKNY3

To: Tunica Albuginea who wrote (4779)	1/19/1998 5:49:00 PM
From: BigKNY3	Read Replies (1) \| Respond to of 23519

TA: <<Next, we, ( you a me, Zebra Cacaito MissLil ?), are going to have to correct line by line Big K's post. I'll start with 1st paragraph: <<Although it accounts for only 2% of the total weight of the body, the brain receives the largest proportion of cardiac output (16-20% of the body's blood).>>Correction #1: largest amount of cardiac output goes to the kidney, 25%; brain only gets 15%>> TA: Dueling blood flows and cardiac output! I guess the answer really lies in which reference source you choose to use. Here's a vote for the liver: Review of Medical Physiology, 17th Ed., Ganong; Appleton and Lange, 1995: Table 32 labeled : Resting Blood Flow and O2 Consumption of Various Organs in a 63 kg Adult Male with a Mean Arterial Blood Pressure of 90 mm Hg [the following represents one column from table]: .........................% of Total Cardiac Output Liver:...................27.8% Kidney:................23.3 Skeletal Muscle:..15.6 Brain:.................. 13.9 Skin:................... 8.6 Heart Muscle:...... 4.7 Rest of body:...... 6.2 All my best!! BigKNY3