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Biotech / Medical : Zonagen (zona) - good buy? -- Ignore unavailable to you. Want to Upgrade?

To: BDR who wrote (1917)	1/21/1998 11:13:00 PM
From: khrnyc	Read Replies (3) \| Respond to of 7041

Dear Dale, Thanks for pointing that out to me. To be more clear, Vasomax is a rapidly dissolving tablet containing the active ingrediant phentolamine. It is not a pill that is swallowed. To my understanding, the tablet is placed in the mouth with some water and dissolves rapidly so that it can then be readily absorbed by the oral mucosa. The patent for absorption through the oral mucosa already belongs to Zona. Other companies can't just come in and make a generic version and administer it in this way. Again, this is Zona's competative and proprietary advantage.

To: BDR who wrote (1917)	1/22/1998 8:41:00 AM
From: C. K. Humphries	Respond to of 7041

<<You may read about this study in full in Zona's patent #5,565,466. >> <<I have read the patent. You haven't explained why the company has avoided the use of sub-lingual or buccal absorption as the means of administration and instead used "a pill" to describe their product which 99 out of a hundred people would assume to mean the normal oral route.>> I agree entirely. If the only unique aspect of this old generic drug is the method of speeding up the absorption, why isn't the method even mentioned. It seems to me it would be pertinent to the patent application. Kent