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Biotech / Medical : Biogen -- Ignore unavailable to you. Want to Upgrade?


To: Harold Engstrom who wrote (571)1/22/1998 2:55:00 PM
From: Vector1  Respond to of 1686
 
From Eric Heckt's Jan 20 update regarding the pipeline:
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Product Pipeline Outlook
More importantly, in 1998 several clinical trials should shed light on Biogen's pipeline potential. Biogen will report data on the use of Avonex in brain cancer. Biogen expects to have clinical data for CVT-124 for renal protection and LFA3-TIP for severe psoriasis. A phase II trial of CVT-124 for the intended market will begin in mid-1998 and data could be available in 1Q99. Data is being analyzed for a phase I trial of CD-40 ligand for ITP. Other indications for CD-40 ligand to be explored this year are Lupus and Factor VIII inhibition. The company intends to out-license Gelsolin, as the clinical data did not meet the internal threshold for advancement.



To: Harold Engstrom who wrote (571)1/22/1998 3:07:00 PM
From: Scott  Respond to of 1686
 
Please fill us in when you get an answer. Note: the Stryker safety data would not be very relevant to Biogen's use. Stryker uses it in an insoluble paste that is globbed onto or into a fracture. Nothing gets into the blood. The only tissue that feels the effects is the area of bone touched by the paste. Biogen/CBM injects it as a liquid into the bloodstream, so it hits every organ in the body at significant levels. Big difference in safety considerations.