SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : Zonagen (zona) - good buy? -- Ignore unavailable to you. Want to Upgrade?


To: Dr. Voodoo who wrote (1999)1/23/1998 6:40:00 PM
From: Tunica Albuginea  Respond to of 7041
 
Voodoo, this paper dated 1976.I believe I saw a reference to it in a textbook of cardiology published few years ago where they mentioned using phentolaamine pills for blood pressure therapy but gave it up because of side effects . I think the Editor was a Dr Parmley. I'll try and get the source if I have time.

TA



To: Dr. Voodoo who wrote (1999)1/24/1998 1:19:00 AM
From: poodle  Respond to of 7041
 
Hi, Rob
Thanks for abstract. Looks attractive.(or abstractive?)

<<Does anybody have this paper yet?>>

I think I can get it but not sure that's the most interesting paper I would like to read. Without ZONA's application no one can make final conclusion about their patent games anyway. I can try to get this paper for you, if you like (and got fax).

If you recalculate 5 mg used in the second paper per 5 liters of blood you will get more than 50 times higher concentration than maximun claimed by Dr. Rubin. Given that there is no immediate dilution by whole blood volume anyway and that specific technic was used to prevent immediate drug diffusion from pennis real difference could be much higher. I would greatly appreciate if our friends with MD degrees post their calculations.

I am really curious what information they supplied to the patients. Given known quality of ZONA's documents this one could be extremely ugly.

Regards,

poodle.