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Strategies & Market Trends : 2026 TeoTwawKi ... 2032 Darkest Interregnum -- Ignore unavailable to you. Want to Upgrade?


To: Dr. Voodoo who wrote (154920)3/21/2020 8:46:49 AM
From: sense  Read Replies (1) | Respond to of 217931
 
Wikipedia says: "As with other quinoline antimalarial drugs, the mechanism of action of quinine has not been fully resolved."

I think that's right. I don't find a find a difficulty in the explanation of the anti-malarial functions in de-crystalization of the heme byproducts... sustaining their toxicity... but I find the explanation of the modification of pH a bit unsatisfying.

Read the articles on the gating of Zn concentrations, which is pretty convincing science...

I expect that, along with accelerated trials... we'll probably see more basic science work done to try to better elucidate the functions that inhibit RNA synthase ? Stopping viral replication... if done early, or done at a high enough level, clearly could be a big difference maker... If it works, knowing how it works will be key to generating "better" more quickly ?

It's likely that having sparked this work... we'll break the spell numbing minds into thinking... "its a virus, and there's not much we can do about those"?