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To: longnshort who wrote (1248945)7/22/2020 7:23:55 PM
From: sylvester80  Respond to of 1578177
 
BOMBSHELL: COVID-19 ANTIBODIES DO NOT PROVIDE A LONG TERM PROTECTION BEYOND A FEW MONTHS
apnews.com
Virus antibodies fade fast but not necessarily protection
By MARILYNN MARCHIONE2 hours ago
Research published on Tuesday, July 21, 2020 suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness. (AP Photo/Paul Sancya)

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.

“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.

The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.

Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.

Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.

Researchers found that the antibodies had a half-life of 36 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.

The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.

That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.

“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.

Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.

Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.

Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.

Creech agreed.

“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”

___

Marilynn Marchione can be followed on Twitter at twitter.com

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

___

This story was updated on July 22, 2020, to correct the half-life of coronavirus antibodies, because of an error made by the researchers. It is 36 days, not 73, according to the lead researcher.





To: longnshort who wrote (1248945)7/22/2020 7:37:00 PM
From: sylvester801 Recommendation

Recommended By
pocotrader

  Respond to of 1578177
 
The WORST outcome will be:
#1 to get a NOT FULLY TESTED vaccine that people end up dying from,
#2 that the covid-19 antibodies quickly fade and the person spreads the disease or even dies from re-infection,
and #3 herd immunity is never achieved, as Sweden is proving.

Sweden hoped herd immunity would curb COVID-19. Don't do what we did. It's not working.
Sweden's approach to COVID has led to death, grief and suffering. The only example we're setting is how not to deal with a deadly infectious disease.
usatoday.com



To: longnshort who wrote (1248945)7/22/2020 7:38:04 PM
From: sylvester80  Read Replies (2) | Respond to of 1578177
 
BOMBSHELL: Sweden hoped herd immunity would curb COVID-19. Don't do what we did. It's not working.
Sweden's approach to COVID has led to death, grief and suffering. The only example we're setting is how not to deal with a deadly infectious disease.
usatoday.com

Sweden has often been considered a leader when it comes to global humanitarian issues, regarded as a beacon of light in areas such as accepting refugees and working against global warming. In the COVID-19 pandemic, Sweden has also created interest around the world by following its own path of using a “soft” approach — not locking down, introducing mostly voluntary restrictions and spurning the use of masks.

This approach has been perceived as more liberal and has shown up in “ Be Like Sweden” signs and chants at U.S. protests. Wherever measures have been lenient, though, death rates have peaked. In the United States, areas that are coming out of lockdown early are suffering, and we are seeing the same in other countries as well.

The motives for the Swedish Public Health Agency's light-touch approach are somewhat of a mystery. Some other countries that initially used this strategy swiftly abandoned it as the death toll began to increase, opting instead for delayed lockdowns. But Sweden has been faithful to its approach.

Why? Gaining herd immunity, where large numbers of the population (preferably younger) are infected and thereby develop immunity, has not been an official goal of the Swedish Public Health Agency. But it has said immunity in the population could help suppress the spread of the disease, and some agency statements suggest it is the secret goal.

An unnerving death rate Further evidence of this is that the agency insists on mandatory schooling for young children, the importance of testing has been played down for a long time, the agency refused to acknowledge the importance of asymptomatic spread of the virus (concerningly, it has encouraged those in households with COVID-19 infected individuals to go to work and school) and still refuses to recommend masks in public, despite the overwhelming evidence of their effectiveness. In addition, the stated goal of the Swedish authorities was always not to minimize the epidemic, but rather slow it down, so that the health care system wouldn’t be overwhelmed.



Several authorities, including the World Health Organization, have condemned herd immunity as a strategy. "It can lead to a very brutal arithmetic that does not put people and life and suffering at the center of that equation,” Dr. Mike Ryan, executive director of WHO's Health Emergencies Program, said at a press conference in May.

With COVID-19, don’t only focus on death: Too many Americans are alive and in misery.

Regardless of whether herd immunity is a goal or a side effect of the Swedish strategy, how has it worked out? Not so well, according to the agency’s own test results. The proportion of Swedes carrying antibodies is estimated to be under 10%, thus nowhere near herd immunity. And yet, the Swedish death rate is unnerving. Sweden has a death toll greater than the United States: 556 deaths per million inhabitants, compared with 425, as of July 20.

Sweden also has a death toll more than four and a half times greater than that of the other four Nordic countries combined — more than seven times greater per million inhabitants. For a number of weeks, Sweden has been among the top in the world when it comes to current reported deaths per capita. And despite this, the strategy in essence remains the same.

Learn from Sweden's mistakesIt is possible that the Public Health Authority actually believed that the Swedish approach was the most appropriate and sustainable one, and that the other countries, many of which went into lockdown, would do worse. Perhaps this, and not herd immunity, is the main reason the authorities are desperately clinging to their strategy. Or perhaps an unwillingness to admit early mistakes and take responsibility for thousands of unnecessary deaths plays into this resistance to change. Nevertheless, the result at this stage is unequivocal.



Adopting the Swedish model: Coronavirus doesn't care about public opinion and it still kills

We do believe Sweden can be used as a model, but not in the way it was thought of initially. It can instead serve as a control group and answer the question of how efficient the voluntary distancing and loose measures in Sweden are compared to lockdowns, aggressive testing, tracing and the use of masks.

In Sweden, the strategy has led to death, grief and suffering and on top of that there are no indications that the Swedish economy has fared better than in many other countries. At the moment, we have set an example for the rest of the world on how not to deal with a deadly infectious disease.

In the end, this too shall pass and life will eventually return to normal. New medical treatments will come and improve the prognosis. Hopefully there will be a vaccine. Stick it out until then. And don’t do it the Swedish way.

Sigurd Bergmann, Ph.D., Emeritus Professor, Norwegian University of Science and Technology

Dr. Leif Bjermer. Ph.D., Professor, Respiratory Medicine and Allergology, Lund University

Barbara Caracciolo, Ph.D., in Epidemiology

Marcus Carlsson, Ph.D., Associate Professor of Mathematics, Lund University

Dr. Lena Einhorn, Ph.D., in Virology

Dr. Stefan Einhorn, Ph.D., Professor of Molecular Oncology, Karolinska Institutet

Andrew Ewing, Ph.D., Professor of Chemistry and Molecular Biology, University of Gothenburg

Dr. Manuel Felices, Ph.D., Head of Endocrine Surgery, NÄL Hospital

Dr. Jonas Frisén, Ph.D., Professor of Stem Cell Research, Karolinska Institutet

Marie Gorwa, Ph.D., Professor of Microbiology, Lund University

Dr. Åke Gustafsson, Ph.D., Clinical Microbiology, Uppsala University Hospital

Dr. Olle Isacsson, Ph.D., Professor of Endocrinology, University of Gothenburg

Dr. Claudia Hanson, Ph.D., Associate professor, Global public health, Karolinska Institutet

Dr. Stefan Hanson, Ph.D., International Health, Karolinska Institutet.

Dr. Jan Lötvall, Ph.D., Professor of Clinical Allergy, University of Gothenburg

Dr. Bo Lundbäck, Ph.D., Professor of Epidemiology of Respiratory Diseases, University of Gothenburg

Åke Lundkvist, Ph.D., Professor of Virology, Uppsala University

Dr. Cecilia Söderberg-Nauclér, Ph.D., Professor of Microbial Pathogenesis, Karolinska Institutet

Finn Nilson, Ph.D., Associate Professor of Risk Management, Karlstad University

Andreas Nilsson, Ph.D., Professor of Psychology, University of Gothenburg

Dr. Björn Olsen, Ph.D., Professor of Infectious Diseases, Uppsala University

Jens Stilhoff Sörensen, Ph.D., Associate Professor, School of Global Studies, University of Gothenburg

Jakob Svensson, Ph.D., Scientific Data Analysis, Max Planck Institute, Greifswald

Dr. Anders Vahlne, Ph.D., Professor of Clinical Virology, Karolinska Institutet

Dr. Anders Wahlin, Ph.D., Professor Emeritus of Hematology, University of Umeå



To: longnshort who wrote (1248945)7/22/2020 8:04:19 PM
From: Proud Deplorable  Respond to of 1578177
 
YES! Burn Portland down with all its left wing citizens (this means everyone). Oregonians are just people who couldn't make it in California so they are angry and bring it to the slummy Portland



To: longnshort who wrote (1248945)7/23/2020 7:26:56 AM
From: Brumar892 Recommendations

Recommended By
pocotrader
rdkflorida2

  Read Replies (1) | Respond to of 1578177
 
You can always count on you Trumpers to hate America:

Message #1248946 from longnshort at 7/22/2020 6:41:27 PM

burn the town down i don't care