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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?

To: Tunica Albuginea who wrote (5203)	2/1/1998 5:02:00 PM
From: don roberson	Read Replies (1) \| Respond to of 23519

TA: It seems the negatives concerning the gel or solution coming out during manipulation can also be said for the pellet as it degenerates in the urine. It has the possibility of going out or going toward the bladder. Possibly more so since the "particulates" suspended in the urine are in a more liquid medium than would be in the HVSF gel. Also, if some of both the VVUS product and HVSF expend out before absorbtion then neither one gives 100% of the product to the patient, and the strength of the dosage takes into consideration this fact. It would seem that the gel would have a better chance of absorption than the dissolving pellet, since one is already in the "liquid" form at insertion. And it would be more evenly distributed. Concerning the VVUS patent. I have read it, and yes they seem to have included all aspects of transurethral application, but the specifics of the patent show detailed drawings of the VVUS applicator and the pellet. There is one clause that tries to cover "all transurethral" applications. I think this is the one sentence that is under contention. It may be in the patent, but it may not hold up. The HVSF product may be different enough to enable it to not only patent the "medium" but also the applicator. yes, the applicator issue looks like it is still up in the air. But if it is a viable product...... and VVUS sees it as a viable product....whether they win the contest of the patent or not.......what would be the rational action ...HMMMM????