SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Politics : Formerly About Advanced Micro Devices -- Ignore unavailable to you. Want to Upgrade?


To: Winfastorlose who wrote (1336975)1/6/2022 4:22:32 AM
From: pocotrader  Respond to of 1576164
 
you always post quack loser crap, read some real science for a change

Those who survived COVID-19 and then got vaccinated have more durable antibodies, study finds
TORONTO -- A study of nearly 2,000 vaccinated health-care workers, some of whom had contracted COVID-19, has found that those who survived the virus and then received an mRNA vaccine have a higher number of long-lasting antibodies.

The results of the study were described in a research letter published Monday in the Journal of the American Medical Association.

“This finding adds to our understanding of how immunity against SARS-CoV-2 works, and builds upon an earlier study by our team that showed the mRNA vaccines yielded a robust antibody response, even if a person did not develop significant symptoms following vaccination or did not have a prior SARS-CoV-2 infection,” Aaron Milstone, professor of pediatrics at the Johns Hopkins University School of Medicine and senior author of the study, said in a press release.

In order to study the antibodies, researchers followed 1,960 health-care workers from Johns Hopkins Medicine in Maryland who had received both doses of either the Pfizer-BioNTech COVID-19 vaccine or the Moderna

Of those 1,960 workers, 73 had previously tested positive for COVID-19 prior to being vaccinated.

Researchers split the 73 workers into two further groups to test whether the time between recovering from the infection and getting vaccinated made a difference, dividing them into those who had COVID-19 within 90 days of their first shot, and those who were exposed more than 90 days before their first shot.

All 1,960 participants gave a serum sample at least 14 days after receiving their second shot, and the samples were tested for antibody levels at one month, three months, four-and-a-half months and six months after receiving the second shot.

Those who had a prior infection before getting vaccinated had higher levels of antibodies than those who only were vaccinated, and their antibody levels remained more durable over time.

“We found that health-care workers with prior SARS-CoV-2 infection followed by two doses of mRNA vaccine — therefore, three independent exposures to the S1 spike protein — developed higher antibody levels than those with vaccination alone,” Diana Zhong, M.D., an infectious diseases fellow at the Johns Hopkins University School of Medicine and lead author of the study, said in the release. “The relative differences were 14 per cent higher at one month following the second vaccine dose, 19 per cent at three months and 56 per cent at six months.” In addition, those who contracted COVID-19 more than 90 days before their first shot had higher antibody levels post-vaccination than those who contracted COVID-19 within 90 days of the first dose.

“This suggests that a longer interval between infection and first vaccine dose may enhance the antibody response,” Milstone said.

Researchers acknowledged that the study had limits, such as the smaller proportion of participants who had COVID-19 in the past, and the fact that they only measured antibody production levels, and not neutralization titers in the blood.

It's important to note that the findings don’t suggest contracting COVID-19 before getting vaccinated. Other research has shown that the virus can cause severe infection and even death in people of any age or health level, and doctors still don’t fully understand the long-lasting effects of the virus on the human body. But the new study does reinforce that those who were infected with COVID-19 previously would benefit from receiving a vaccine.

Researchers stated in the release that further research is needed to understand “the interplay between natural or vaccine derived immunity.”

ctvnews.ca



To: Winfastorlose who wrote (1336975)1/6/2022 4:38:25 AM
From: pocotrader  Read Replies (1) | Respond to of 1576164
 
How Soon Can You Get Vaccinated After Recovering From COVID-19?
Jan. 5, 2022 - Katie McCallum

If you're unvaccinated and recovering from COVID-19 — whether the case is mild or more severe — you might be wondering how soon before you can take the necessary step to prevent a recurrence: getting vaccinated.

The risk of reinfection — yes, it is possible — is not insignificant. The data show that unvaccinated adults are twice as likely to get COVID-19 a second time than those who get vaccinated after recovering.

"Anyone who can get vaccinated, regardless of whether or not they've had COVID-19, should do so," says Dr. Robert Phillips, executive vice president and chief physician executive at Houston Methodist. "At this point, there are just too many unknowns regarding how durable and reliable natural immunity is to feel confident about the protection it may offer."

Vaccine-induced immunity offers incredibly effective protection against severe illness from COVID-19 — even against the more infectious omicron variant.

And COVID boosters provide even more protection. This means anyone who is eligible should consider getting their booster as soon as possible.

So if you have COVID-19 and are ready to get vaccinated or are wondering when you can get your booster, here's what you need to know:

How soon can you get vaccinated after recovering from COVID-19? "After testing positive for COVID-19, you will need to postpone getting vaccinated until your symptoms have resolved and you've met the criteria for discontinuing isolation," says Dr. Phillips. "This timeline can vary by person, depending on your symptom severity and the treatments you may have received."

The criteria for ending isolation varies from person to person, so be sure you understand what your isolation timeline needs to look like.

"Someone with an asymptomatic COVID-19 case can get vaccinated as soon as their isolation ends. You don't need a negative viral test before vaccination," says Dr. Phillips.

One caveat: If you received monoclonal antibodies or convalescent plasma, you will need to wait 90 days before getting the vaccine.

"People who received either of these antibody treatments will need to wait about three months before getting vaccinated," says Dr. Phillips. "The reason for this is that the antibodies in these treatments might hinder you from developing a complete immune response towards the vaccine."

Talk to your doctor if you're not sure which exact COVID-19 treatments you received during your illness.

How soon can you get a COVID booster after having COVID-19? If you have recently had a COVID-19 breakthrough infection and are 16+, it's recommended that you get your COVID booster once your symptoms have resolved and you've met the criteria to end isolation — and the recommended time has elapsed since your primary series of either Pfizer (5 months), Moderna (6 months) or J&J (2 months).

Vaccinated people who received monoclonal antibodies as part of their COVID-19 treatment plan will need to wait 90 days before getting a COVID booster.

houstonmethodist.org



To: Winfastorlose who wrote (1336975)1/6/2022 4:55:24 AM
From: pocotrader  Respond to of 1576164
 
COVID Natural Immunity: What You Need to Know

Lisa Maragakis, M.D., M.P.H.




Gabor David Kelen, M.D.


If you had COVID-19, you may wonder if you now have natural immunity to the coronavirus. And if so, how does that compare to protection offered by the COVID-19 vaccinations?

Lisa Maragakis, M.D., M.P.H., senior director of infection prevention, and Gabor Kelen, M.D., director of the Johns Hopkins Office of Critical Event Preparedness and Response, help you understand natural immunity and why getting a coronavirus vaccine is recommended, even if you’ve already had COVID-19.

What is immunity? Immunity is your body’s ability to protect you from getting sick when you are exposed to an infectious agent (“germ”) such as a bacterium, virus, parasite or fungus.

Immunity is a complex process that involves a lot of moving parts. Your body produces a variety of different cells that fight invading germs. Some of these release special proteins called antibodies into your blood stream. These antibody producing cells can “remember” a particular germ so they can detect its presence if it returns and produce antibodies to stop it.

What is natural immunity? Natural immunity is the antibody protection your body creates against a germ once you’ve been infected with it. Natural immunity varies according to the person and the germ. For example, people who have had the measles are not likely to get it again, but this is not the case for every disease. A mild case of an illness may not result in strong natural immunity. New studies show that natural immunity to the coronavirus weakens (wanes) over time, and does so faster than immunity provided by COVID-19 vaccination.

What is vaccine-induced immunity for COVID-19? Vaccine-induced immunity is what we get by being fully vaccinated with an approved or authorized COVID-19 vaccine. Research indicates that the protection from the vaccines may wane over time so additional doses (boosters) are now authorized for certain populations. These boosters can extend the powerful protection offered by the COVID-19 vaccines.

If I have natural immunity do I still need a COVID vaccine? Yes, the COVID-19 vaccines are recommended, even if you had COVID-19. At present, evidence from Johns Hopkins Medicine and the U.S. Centers for Disease Control and Prevention (CDC) supports getting a COVID-19 vaccine as the best protection against getting COVID-19, whether you have already had the virus or not.

Here are recent research studies that support getting vaccinated even if you have already had COVID-19:

Vaccines add protection.

  • The U.S. Centers for Disease Control and Prevention (CDC) released a report on Oct. 29, 2021, that says getting vaccinated for the coronavirus when you’ve already had COVID-19 significantly enhances your immune protection and further reduces your risk of reinfection.
  • A study published in August 2021 indicates that if you had COVID-19 before and are not vaccinated, your risk of getting re-infected is more than two times higher than for those who got vaccinated after having COVID-19.
  • Another study published on Nov. 5, 2021, by the U.S. Centers for Disease Control and Prevention (CDC) looked at adults hospitalized for COVID-like sickness between January and September 2021. This study found that the chances of these adults testing positive for COVID-19 were 5.49 times higher in unvaccinated people who had COVID-19 in the past than they were for those who had been vaccinated for COVID and had not had an infection before.
  • A study from the CDC in September 2021 showed that roughly one-third of those with COVID-19 cases in the study had no apparent natural immunity.
Immunity varies for individuals: Immune response can differ in people who get COVID-19 and recover from the illness. The FDA-authorized and approved vaccines have been given to almost 200 million people in the U.S. alone, and have strong data supporting their effectiveness.

Delta variant and future coronavirus variants: Hospitalizations of people with severe COVID-19 soared over the late summer and into fall as the delta variant moved across the country. People infected with earlier versions of the coronavirus and who haven’t been vaccinated might be more vulnerable to new mutations of the coronavirus such as those found in the delta variant. To date, the authorized vaccines provide protection from serious disease or death due to all currently circulating coronavirus variants.

Should I hold off getting a COVID vaccine to see if there is new research on natural immunity? Holding off on getting vaccinated for COVID-19 is not a good idea. Here’s why:

  1. Getting COVID-19 is very risky and can result in long-term disease, lasting organ damage, hospitalization or even death.
  2. Even if your own infection is mild, you can spread it to others who may have severe illness and death.
  3. The authorized and approved vaccines are safe and highly effective against severe illness or death due to COVID.
  4. Risks of COVID-19 vaccine side effects are extremely low.
For the reasons above, the CDC recommends and Johns Hopkins Medicine agrees that all eligible people get vaccinated with any of the three FDA-approved or authorized COVID-19 vaccines, including those who have already had COVID-19.

Johns Hopkins Research on Natural Immunity for COVID-19 and COVID Vaccines Johns Hopkins has conducted a large study on natural immunity that shows antibody levels against COVID-19 coronavirus stay higher for a longer time in people who were infected by the virus and then were fully vaccinated with mRNA COVID-19 vaccines compared with those who only got immunized. (The results of the study were published in a letter to the Journal of the American Medical Association on Nov. 1, 2021.)

The data show that one month after they got their second shot, participants who had had COVID-19 more than 90 days before their first shot had adjusted antibody levels higher than those who had been exposed to the coronavirus more recently than 90 days. Three months after the second coronavirus vaccine, the antibody levels were even higher: 13% higher than those who were exposed to the virus less than or equal to the 90-day mark.

These study results suggest that natural immunity may increase the protection of the shots when there is a longer time period between having COVID-19 and getting vaccinated.


Published on November 23, 2021
Related
COVID-19: Vaccines Myth Versus Fact Booster Shots and Third Doses for COVID-19 Vaccines COVID Omicron Variant: What You Need to Know Is the COVID-19 Vaccine Safe?