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Biotech / Medical : 2022 Biotech Charity Contest -- Ignore unavailable to you. Want to Upgrade?


To: technetium who wrote (139)6/23/2022 11:30:20 AM
From: Bladerunner17  Read Replies (1) | Respond to of 267
 
FSTX to be acquired.

invoX Pharma to Acquire F-star Therapeutics, Inc. a Pioneering Next Generation Bispecific Discovery Platform and Clinical Programs

F-star Therapeutics, Inc.
Thu, June 23, 2022, 4:30 AM

In this article:

FSTX
+59.34%

SBHMY
0.00%

SBMFF
0.00%

SRPT
+2.25%



F-star Therapeutics, Inc.
Proposed ~US$161 million all-cash acquisition to accelerate invoX’s strategy to build Sino Biopharm’s International Biopharmaceutical R&D Platform outside of China, transforming the lives of patients worldwide

The transaction demonstrates the strength of F-star’s differentiated bispecific antibody technology and provides backing from a top 40 global pharmaceutical company to accelerate growth and unlock potential

F-star’s unique next-generation tetravalent (2+2) bispecific antibody platform complements Sino Biopharm’s existing capabilities and reinforces its global oncology pipeline

LONDON, June 23, 2022 (GLOBE NEWSWIRE) -- invoX Pharma (“invoX”), a wholly owned subsidiary of Sino Biopharmaceutical Limited (“Sino Biopharm”) (HKEX 1177 HK), focused on research and development (R&D) and business development activities outside of China, and F-star Therapeutics, Inc. (“F-star”) (NASDAQ:FSTX), a clinical-stage biopharmaceutical company pioneering bispecifics in immunotherapy so more people with cancer can live longer and improved lives, today announced that the companies have entered into a definitive agreement whereby invoX will acquire all of the issued and outstanding shares of F-star common stock for $7.12 per share. The proposed acquisition values F-star at approximately $161 million. The transaction has been unanimously approved by the invoX and F-star Boards of Directors and is expected to close in the second half of 2022.

F-star’s proprietary platform technology pioneers the use of tetravalent (2+2) bispecific antibodies that enable the simultaneous targeting of two different antigens and a unique set of pharmacology to deliver focused, potent and safe immune activation in the tumor microenvironment. Four programs are progressing in clinic, three based on F-star’s tetravalent platform and one next generation STING agonist, with multiple further undisclosed programs in development. These programs represent potentially first- and best-in-class drug candidates for many areas of unmet medical need, including patients with cancer and other serious diseases who have few other options available. Leveraging its modular antibody technology, F-star has forged collaborations with major international biopharma companies across a wide range of therapeutic areas including oncology, immunology and neurology.

invoX, established in 2021 in the United Kingdom, is Sino Biopharm’s international expansion platform, focusing on R&D and business development activities outside of China, with a core focus on oncology and respiratory therapeutics. F-star will form a key element of invoX’s strategy to accelerate Sino Biopharm’s development of innovative medicines to transform the lives of patients worldwide, complementing its existing R&D platforms and pipeline.

Ben Toogood, Chief Executive Officer of invoX commented: “Today’s proposed acquisition is aligned with invoX’s strategy to become a fully integrated biopharmaceutical company with an advancing pipeline of innovative products addressing unmet healthcare needs, worldwide. We are excited to welcome F-star employees and look forward to working with them as we invest in the company to progress and grow its clinical pipeline to realize the full potential of the platform.”

Eliot Forster, Chief Executive Officer of F-star said: “We believe our tetravalent bispecifics offer the best approach to tackle hard-to-treat cancers and other serious diseases, with the ambition to deliver longer and improved lives for patients. Today’s announcement is good news for F-star, for our shareholders and, of course, for patients. This transaction enables greater and longer-term opportunities to develop the F-star platform and accelerate delivery of our novel medicines as we work together towards a future free from cancer and other serious diseases. I’d like to thank the fantastic team at F-star as well as our partners for all their hard work, support and dedication and I’m delighted to share this exciting development.”

Transaction Terms

Under the terms of the merger agreement, invoX, a wholly owned subsidiary of Sino Biopharm, will commence a tender offer within the next 10 business days to acquire all of the issued and outstanding shares of F-star common stock for a price of US$7.12 per share in cash upon the completion of the offer. The transaction is expected to complete in the second half of 2022, subject to certain customary closing conditions, including the tender by F-star stockholders of greater than 50 percent of the issued and outstanding shares of F-star common stock and required regulatory approvals, including the expiration of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 and other customary closing conditions. Following the closing of the tender offer, invoX will acquire any shares of F-star that are not tendered in the tender through a second-step merger under Delaware law at the tender offer price.

Bladerunner



To: technetium who wrote (139)6/26/2022 2:45:17 PM
From: technetium  Read Replies (1) | Respond to of 267
 
Well this has certainly been an unusual week. Fortunately, it seems to have been an unusually good week for both the broader market (up 7.5% for the NASDAQ composite) and the biotech indices, which did even better, up 9.7% and 14%. And this has been even broader: 81% of the contest selected stocks were in the black for the week. In some cases it wasn’t just irrational exuberance, there was some sort of explanation. Last week’s top performer, FSTX, which is carried by five portfolios, owed its 87% rise to a proposed cash acquisition. IPIX made a 74% jump probably because of strong in vitro results for an anti-COVID antiviral.

In terms of the portfolio performance, every contestant was in the black for the week, running from up just 0.3% to 29% for BLADERUNNER, thanks to a $20,000 stake in FSTX. Our current top YTD contestant, DIEGOSAN, has lept to being only 5.4% in the red. More weeks like this? Who knows, portfolios might make an actual positive return by the end of the contestant. Special congratulations for ETHAN H, and TAMBORELLI, for their return to the top 10 after three weeks absence.



Report Time Ranges





From

To

Recent

6/17/22

6/24/22

YTD

12/31/21

Index Performance



Symbol

Recent

YTD



^IXIC

7.49%

-25.81%

^NBI

9.66%

-18.59%

^SPSIBI

13.94%

-31.07%

Share Performance

Recent

YTD

Top 5

Bottom 5

Top 5

Bottom 5

FSTX

87.390%

PRDS

-29.098%

OPTN

132.10%

GNCA

-98.56%

IPIX

74.026%

KZIA

-19.734%

CBIO

65.21%

PRQR

-91.51%

IPHA

44.500%

CRVS

-17.143%

MACK

49.62%

VLON

-91.47%

CLVS

44.068%

AYLA

-15.079%

VRTX

33.22%

PTE

-88.62%

WVE

43.147%

AMBS

-12.903%

ESPR

29.40%

AYLA

-87.43%



Top 10 Portfolio YTD

YTD(Portfolio - SPSIBI)

Rec

Rec(Port. - SPSIBI)

DIEGOSAN

-5.39%

25.68%

10.129%

-3.814%

DEW DILIGENCE

-18.74%

12.33%

10.695%

-3.248%

KMASTRA

-24.23%

6.84%

20.585%

6.642%

TECHNETIUM

-25.95%

5.12%

11.512%

-2.430%

GENEGURU

-29.50%

1.57%

0.758%

-13.185%

BIOSCIENTISTSA

-30.80%

0.27%

7.476%

-6.466%

ROCKY9

-32.81%

-1.74%

11.042%

-2.901%

TAMBORELLI

-33.52%

-2.45%

16.632%

2.690%

A.J. MULLEN

-33.53%

-2.46%

5.145%

-8.798%

ETHAN H

-33.89%

-2.82%

14.185%

0.242%

Average and Median Portfolio Performance



Avg Recent

Avg YTD

Median Recent

Median YTD



$6,313

-37.47%

BIO-TITAN

$6,557

MOPGCW

-38.48%

11.56%

DEW DILIGENCE

10.817%



Rick Shafer