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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?


To: RXGOLF who wrote (14562)2/11/1998 12:18:00 AM
From: Henry Niman  Read Replies (2) | Respond to of 32384
 
I believe that Taxol was recently approved for KS also. See Panretin oral treatment of KS section of home.att.net
New therapies shrink lesions, reduce pain and other symptoms

The past few months have brought encouraging news about several
treatments for Kaposi's sarcoma (KS), both approved and
experimental. First, the F.D.A. approved Bristol-Myers Squibb's
anti-cancer drug Taxolr for use against KS. Clinical studies have
demonstrated that Taxol, while it does not cure KS, shrinks the
lesions associated with this skin cancer and reduces the pain caused
by the lesions. Researchers report that Taxol has proven effective in
reducing lesion size in some people with KS who have failed to
respond to other therapies.

Next, doctors from the University of California at San Francisco
reported that five patients with KS experienced improvement when
they began taking the protease inhibitor ritonavir (Norvirr). In all
five cases ritonavir was added to whatever combination of antiviral
drugs the patients were already taking. It is impossible to say, at this
point, if the response that was seen in this handful of patients was a
specific to ritonavir or was yet another demonstration of the potency
of the protease inhibitors as a class. It remains to be seen if ritonavir
alone will prove to be a useful weapon against KS.

Finally, Allergan Ligand Retinoid Therapeutics reported promising
results for its experimental KS therapy, panretin topical gel, and
applied for F.D.A. approval. Allergan Ligand is also testing an oral
version of panretin.