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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?

To: Henry Niman who wrote (14629)	2/11/1998 6:06:00 PM
From: Arthur Radley	Read Replies (1) \| Respond to of 32384

Henry, Realizing this is only animal models, it is still exciting news. With a 72% complete regression it certainly indicates that it works in rats. With the 72% number for Targretin and only 33% for Tamoxifen, can you determine if the Tamoxifen number is human or animal results. If the 33% number is animal and now is approved for humans, you would just have to think that Targretin will prove to be valid for humans(I HOPE, I HOPE). PS: Just found the answer by reading further in the news release. The tamoxifen number was also animal. One additional tidbit of information. I am holding some Feb 15 call options and needless to say for the past few months there has been no bid price offered for them,only an ask price of 3/16. Here with the stock sitting on 13.25 and 1.75 out of the money and expiring next week, suddenly today there was a bid of 1/16 for the options and at the close they had upped the bid to 1/8. Makes you think that someone knew that news of a major nature was coming.

To: Henry Niman who wrote (14629)	2/11/1998 6:59:00 PM
From: Andrew H	Read Replies (1) \| Respond to of 32384

>>and we now have determined that Targretin is effective in the treatment of well-established tumors," according to Richard Heyman, Ph.D., Senior Director of Ligand's department of Retinoid Research.<< This is big news, however the market and the barnyard leaders respond. More than twice as effective as the leading treatment!! And with virtually none of the nasty side effects. If it doesn't move the stock now, it will before too long. Maybe it can help that rodent, Mr. Tucker?