To: technetium who wrote (227 ) 12/17/2022 11:55:23 AM From: technetium 1 RecommendationRecommended By BulbaMan
Read Replies (2) | Respond to of 267 An up and down week (ending down) for the market generally, due to (they say) inflation, jobs numbers, and fed interest rates. Biotech, on the other hand managed to have a more positive performance. The composite indices were up +0.3% (NASDAQ Biotech index) and +1.9% (S&P Biotech index). Again this week, the S&P Biotech did substantially better than the NASDAQ Biotech, which has not been the norm, as you can see in their YTD performances of -28% and -10% respectively. The big winner for the week was WVE, up +41%, apparently on the announcement of a strategic collaboration with GSK, which by some analysts figures, might be worth up to $3.3 billion for WVE in milestone payments. (GSK is GlaxoSmithKline, which have deep enough pockets to make those payments). DYN’s +24% seemed in response to a number of positive analyst reports, though I’m not sure how positive the message is when the report that starts “There’s no doubt that money can be made b owing shares of unprofitable businesses." Number five for the week, CABA, up +22%, continued its gains noted in last week’s report, in response to a very successful $35 million dollar stock and warrant sale. On the other side, SNPX had a very bad week, -52%, though just before the close Friday it released a very positive report on results for a Phase 2 Clinical trail on their drug for treating advanced Alzheimer’s disease. Perhaps a more consequential loser was number five MACK, shedding -21%, most of it Friday . It is still comfortably in the number one spot YTD (+179%), though not the over +200% return of previous weeks. This was another week when the contest portfolios couldn’t match the biotech indices, the median portfolio dropping -0.6% for the week. In the YTD performance, things tightened up considerably between first place DIEGOSAN, and coming up fast second place GENEGURU, their portfolio values now separated by less than $900. GENEGURU’s good week put them back in the black YTD. In percentage terms, RAJU_BIJLEE had the best week overall, up +13.6%. JFM WINTER should be congratulated for his return to the top ten YTD list after a 5 month absence. Only two more reports to go. I hope everyone is having a happy, and healthy, holiday season.Report Time Ranges From To Recent 12/9/2022 12/16/2022 YTD 12/31/2021 Index Performance Symbol Recent YTD ^IXIC -2.72% -31.57% ^NBI 0.27% -9.99% ^SPSIBI 1.89% -27.55% Share Performance Recent Change as % of Initial Price YTD Top 5 Bottom 5 Top 5 Bottom 5 WVE 41.401% SNPX -51.704% MACK 179.28% GNCA -99.66% DYN 23.549% BTI.V -48.148% FENC 125.23% PLXP -97.63% RIGL 22.909% ACET -44.997% BIOA-B.ST 119.47% CLVS -97.05% HROW 22.685% PRTC -21.378% CBIO 109.85% ATHX -96.40% CABA 21.900% MACK -20.972% PCVX 92.52% OTIC -95.67% Top Ten Portfolios Top 10 Portfolio YTD YTD(Portfolio - SPSIBI) Rec Rec(Port. - SPSIBI) Rec. Change Total Value DIEGOSAN 2.82% 30.37% -0.87% -2.760% -$899.84 GENEGURU 1.94% 29.49% 4.29% 2.393% $4189.18 MOPGCW -9.58% 17.97% 2.73% 0.838% $2403.32 TECHNETIUM -19.29% 8.26% -0.24% -2.130% -$192.26 BRENDAN_49 -23.97% 3.59% 3.63% 1.734% $2661.25 DEW DILIGENCE -25.97% 1.58% -1.41% -3.306% -$1061.01 BMAZ001 -26.32% 1.23% 2.33% 0.440% $1679.28 A.J. MULLEN -27.54% 0.02% 0.22% -1.672% $159.63 HORSEINALFALFA -27.98% -0.43% -1.16% -3.051% -$843.85 JFM WINTER -30.08% -2.53% 0.18% -1.712% $125.74 Average and Median Portfolio Performance Avg Recent Avg YTD Median Recent Median YTD -$388 -37.16% ARTHUR RADLEY -$320 BIO-TITAN -37.75% -0.86% ARTHUR RADLEY -0.595%