So this week we can see that 2024 is probably not a Brave New World of more or less continuous gains for biotech stocks. This week basically turns all that good news from the previous week on its head. It’s been a good week (+2.3%) for the NASDAQ composite (and a new record for the S&P 500). Even if the previous week was better for the NASDAQ (+3.1%), but it was this week that put the YTD performance into the black (+$2k). The NASDAQ biotech index dropped -1.7%, down to +$500, while the S&P biotech index cratered (-3.6%) through to a current YTD loss (-$2.4k).
Looking at the contest stocks, in first place for the week is a familiar one from last year, JSPR, +33.3% of its original price, leaping to second place in the YTD return (+40%), with no obvious explanation in the Yahoo Finance links, other than a press release of “Highlights (of) Recent Accomplishments” two weeks ago on Jan 5. Third place for the week, ACRS (+20%), may have owed its bump to an appointment of a new interim CEO. EOLS performance, positioning it in fifth for the week (+12%) is probably the response to 4th quarter earnings released on Thursday. In addition to JSPR, the week brought two others onto the top 5 YTD performers: SLDB and PYXS.
The worst performer for the week was SNGX (-35%), in spite of trumpeting great phase II results earlier in the week. The second worst was PMN (-32%), perhaps a correction to the outstanding +124% gain of the previous week. Even with the downturn the PMN YTD return of +92% still holds the top position in that ranking. The fifth worst stock for the week was FHTX (-22%) just another insult to two weeks of injury so that it is now the second worst YTD performer (-40%).
The portfolios told a bitter tale this week, with the average portfolio losing -$4.9k and swinging into the red YTD (-$2.2k). Every portfolio posted a loss for this week, and only five portfolios are still in the black YTD, down from twelve only a week ago.
The best was JACK HARTMANN, losing only -$490, and joining the YTD top 8 in seventh place, from twelfth, as a result. The -$1.5k loss in second place for the week, TRACE I11, allowed them to watch five other portfolios post bigger losses, to move from seventh to second place in the YTD returns as well. NOTABOT had the seventh best performing portfolio for the week (-$3.1k_, allowing it to move their YTD position from eight to fifth (a virtual wash return of +$87 and change). ARTHUR RADLEY, at fifth for the week (-$2.1k) joins the YTD top perfumers in eighth place.
Even with the good performance in JSPR, the only porfolio holding it, BLADERUNNER, had the fourth worst return for the week, with every other of their choices a loser, dropping them one place to third (YTD). The third worst for the week was BULBAMAN (-$8.4k) thanks to holding BOTH of the worst two stocks for the week, SNGX and PMN. Even so, the big returns they had the previous week meant that they are still the best YTD performer (+$12.8k), and with a lead of $11.2k over TRACE I11. The second worst for the week was RAJU_BIJLEE (-$9k), which only dropped their YTD position from third to sixth. So even after catastrophe, most are hanging in there.
It’s early days still.
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| 1/12/24
| 1/19/24
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| YTD
| 12/31/2023
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| Index Portfolios’ Performance
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| Symbol
| Recent P/L
| Recent %
| YTD P/L
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| ^IXIC
| $2,253.01
| 2.3%
| $1,995.92
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| ^NBI
| -$1,737.87
| -1.7%
| $598.89
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| ^SPSIBI
| -$3,672.66
| -3.6%
| -$2,416.08
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| Share Performance
| Recent Performance
| YTD Performance
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| Top Five
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| Bottom Five
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| Top Five
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| Bottom 5
| Symbol
| P/L / Initial Price
| Symbol
| P/L / Initial Price
| Symbol
| YTD P/L / Initial Price
| Symbol
| YTD P/L/ Initial Price
| JSPR
| 33.3%
| SNGX
| -34.8%
| PMN
| 92.2%
| VERU
| -48.6%
| TNYA
| 23.8%
| PMN
| -32.2%
| JSPR
| 39.7%
| FHTX
| -40.5%
| ACRS
| 20.6%
| VINC
| -25.4%
| ARDX
| 33.5%
| CNSP
| -38.6%
| SYRE
| 12.6%
| ALT
| -24.4%
| SLDB
| 31.9%
| RVNC
| -35.6%
| EOLS
| 12.3%
| FHTX
| -22.0%
| PYXS
| 29.4%
| PACB
| -32.8%
| Average and Median Portfolio Performance
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| Recent P/L
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| YTD P/L
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| Avg.
| Median
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| Avg
| Median
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| -$4,939.69
| -$5,318.01
| KATHLEEN
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| -$2,213.85
| -$635.54
| DART LANZER
| Top Seven Portfolio Performances
| Top Recent Performers
| Top YTD Performers
| Contestant (Prev. Rank)
| Recent P/L
| P/L vs. ^SPSIBI
| YTD P/L (Rank)
| Contestant (Prev. Rank)
| YTD P/L
| vs. Top Portfolio
| P/L vs. ^SPSIBI
| Rec. P/L (Rank)
| 1 - JACK HARTMANN (14)
| -$488.16
| $3,184.50
| -$438.31 (7)
| 1 - BULBAMAN (1)
| $12,810.19
| ——
| $15,226.28
| -$8,372.96 (15)
| 2 - TRACE I11 (9)
| -$1,530.60
| $2,142.06
| $1,641.99 (2)
| 2 - TRACE I11 (7)
| $1,641.99
| $11,168.20
| $4,058.07
| -$1,530.60 (2)
| 3 - DEW_DILIGENCE (16)
| -$1,755.13
| $1,917.53
| -$1,905.08 (11)
| 3 - BLADERUNNER (2)
| $1,638.26
| $11,171.94
| $4,054.34
| -$7,809.50 (14)
| 4 - A. J. MULLEN (17)
| -$1,975.20
| $1,697.46
| -$11,596.37 (16)
| 4 - JR_95 (4)
| $609.06
| $12,201.13
| $3,025.14
| -$5,917.09 (11)
| 5 - ARTHER RADLEY (4)
| -$2,086.72
| $1,585.93
| -$488.97 (8)
| 5 - NOTABOT (8)
| $87.24
| $12,722.95
| $2,503.33
| -$3,078.10 (7)
| 6 - ERIKOTTO (10)
| -$3,002.69
| $669.96
| -$2,040.64 (12)
| 6 - RAJU_BIJLEE (3)
| -$214.67
| $13,024.86
| $2,201.42
| -$8,997.07 (16)
| 7 - NOTABOT (11)
| -$3,078.10
| $594.56
| $87.24 (5)
| 7 - JACK HARTMANN (12)
| -$438.31
| $13,248.50
| $1,977.78
| -$488.16 (1)
| 8 - DART LANZER (5)
| -$4,686.14
| -$1,013.48
| -$635.54 (9)
| 8 - ARTHER RADLEY (10)
| -$488.97
| $13,299.16
| $1,927.12
| -$2,086.72 (5)
| Top Portfolios’ Contents
| Top Recent Performance Portfolio (JACK HARTMANN)
| Top YTD Performance Portfolio (BULBAMAN)
| Symbol (Rank)
| Initial Allocation
| Value/Total | ROI
| YTD Stock P/L
| Recent Stock P/L
| % Current Price Change for $1,000 P/L
| Symbol (Rank)
| Initial Allocation
| Value/Total | ROI
| YTD Stock P/L
| Recent Stock P/L
| % Current Price Change for $1,000 P/L
| APGE
| 10.00%
| 12.1% | 20.6%
| $2,057.98
| $622.76
| 8.3%
| CU6.AX
| 20.00%
| 21.2% | 19.8%
| $3,967.85
| $404.44
| 4.2%
| ARWR
| 10.00%
| 11.1% | 10.3%
| $1,029.41
| -$875.82
| 9.1%
| CYTH
| 10.00%
| 9.0% | 1.9%
| $188.68
| -$1,509.43
| 9.8%
| AUPH
| 10.00%
| 8.9% | -11.0%
| -$1,101.22
| $289.21
| 11.2%
| LRMR
| 10.00%
| 8.3% | -5.9%
| -$593.41
| -$725.27
| 10.6%
| BNTX
| 10.00%
| 9.3% | -6.9%
| -$693.58
| -$506.92
| 10.7%
| PMN
| 10.00%
| 17.0% | 92.2%
| $9,217.39
| -$3,217.39
| 5.2%
| BRNS
| 10.00%
| 8.7% | -13.3%
| -$1,327.91
| -$433.60
| 11.5%
| SNGX
| 10.00%
| 6.7% | -24.5%
| -$2,450.00
| -$3,476.32
| 13.2%
| CMPS
| 10.00%
| 9.2% | -8.2%
| -$822.86
| -$468.57
| 10.9%
| TCON
| 10.00%
| 7.7% | -12.7%
| -$1,273.56
| -$936.61
| 11.5%
| MRNA
| 10.00%
| 10.1% | 0.3%
| $25.14
| -$628.46
| 10.0%
| TLX.AX
| 15.00%
| 14.4% | 8.0%
| $1,206.22
| $821.63
| 6.2%
| NVCR
| 10.00%
| 9.4% | -6.4%
| -$636.30
| $395.18
| 10.7%
| VKTX
| 15.00%
| 15.6% | 17.0%
| $2,547.02
| $265.99
| 5.7%
| PFE
| 10.00%
| 9.9% | -1.8%
| -$177.14
| -$145.88
| 10.2%
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| SYRE
| 10.00%
| 11.3% | 12.1%
| $1,208.18
| $1,263.94
| 8.9%
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