To: Don Green who wrote (13 ) 2/16/2024 11:31:22 AM From: Don Green Read Replies (1) | Respond to What is consider normal PSA levels after having radiation treatment for prostate cancer Post-Radiation PSA Behavior: Slow Drop: Unlike surgery where PSA drops quickly to undetectable, radiation causes a gradual decline, typically reaching its lowest point (nadir) around 18 months to 2 years after treatment.Residual PSA Production: Even after successful treatment, normal prostate cells remain and can produce some PSA, preventing a complete drop to zero. Interpreting PSA Levels: Nadir Level: Generally, a nadir below 1 ng/mL indicates successful treatment, especially if maintained over time. Some studies even suggest aiming for below 0.5 ng/mL for optimal results.Increase from Nadir: A rise of 2.0 ng/mL or more from the nadir within a year can be concerning and warrant further investigation, potentially indicating cancer recurrence.Age and Gleason Score: Younger age and higher Gleason score (aggressiveness of cancer) may necessitate stricter PSA thresholds for monitoring. Remember: These are general guidelines, and individual interpretations depend on your specific circumstances and treatment details. Your doctor will monitor your PSA regularly and assess its changes in conjunction with other factors for accurate evaluation. Do not interpret PSA levels alone and always consult your doctor for a comprehensive understanding of your situation and any necessary follow-up steps. Here are some helpful resources for further information:
