To: Eric who wrote (1462774 ) 6/14/2024 1:35:50 PM From: maceng2 Read Replies (1) | Respond to << Many, many more classes than just your one class in high school. >> Sure. So, perhaps you could be kind enough to interpret this paper for those who are not so well educated in the subject of biology? << There is also concern that vaccine inoculation may intensify the disease process for certain infections, including dengue and respiratory syncytial virus, or that infections may show signs of vaccine resistance [ Citation33–35 ]. Dengvaxia inoculation has been shown to enhance the dengue infection and intensified the disease process, as vaccine inoculation failed to induce cellular immunity against dengue virus [ Citation36 ]. In addition, Dengvaxia includes an antigen (the membrane protein) to elicit the ‘antibody-dependent enhancement’ process to intensify the disease process [ Citation37 ]. Dengue vaccine, therefore, demonstrates the risks of using human vaccine without adequate optimization that, rather than providing defense, becomes a cause of distress. Again, ‘antibody-dependent enhancement’ and viral mutations may contribute to increase disease burden associated with repeated vaccine inoculation, reducing vaccine effectiveness. Carefully designed clinical studies are needed to confirm these effects. >>Full article: Repeated vaccination and ‘vaccine exhaustion’: relevance to the COVID-19 crisis (tandfonline.com)
