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To: russet who wrote (39062)1/18/2025 10:31:00 AM
From: Stock Puppy1 Recommendation

Recommended By
Thomas M.

  Read Replies (3) | Respond to of 39305
 
I am saying that one must be very cautious using DMSO.



You must cleanse the skin before applying, but most toxins are high molecule weight so will not be transfered through the skin.

Interesting - what would be considered high molecular weight for this purpose?

Greater than 300 Da? 600? 1500?

There are plenty of small molecule toxins out there - some which are not generally considered toxic since the body has barriers to absorption which the DMSO bypasses.
So yes as you say, application has to be careful - skin must be carefully cleaned.

On another note,
Interestingly, often when drugs are tested for initial viability, they are solvated in DMSO.
Not for any effect of the DMSO, but because it's easy to dissolve most things in it.



To: russet who wrote (39062)1/18/2025 12:12:42 PM
From: teevee1 Recommendation

Recommended By
Hugh Bett

  Respond to of 39305
 
I would add that DMSO in contact with water is an exerthermic reaction Before using on skin, in addition to skin being clean and DRT, dilute liquid by 1/3 by adding to water . Similar to acid, make sure to add the DMSO to water, not the other way round.