To: Sergio H who wrote (1220 ) 2/28/1998 2:58:00 AM From: Amigo Mike Read Replies (1) | Respond to of 29382
Ok All, Here is some interesting news for everyone. It is a recent article in a very well respected business journal. Read very carefully. LITTLE KNOWN PATHOGEN COULD MEAN HUGE REVENUE BOOST FOR ANTEX BIOLOGICS. Biotech Firm is Working on Vaccine for Campylobacter. If Successful, Product Could Be Worth $200M - $400M/Year. By: Shell Schwartz - Daily Record Business Writer Toss around the terms "salmonella" and "E-Coli" and most people not only are familiar with the food-borne pathogens, but also can spout off their symptoms. And yet, Campylobacter - now the leading cause of food poisoning in this country - has gone largely unnoticed. "Not many people are aware of this [bacteria], but it is definitely on the emerging disease list," said Vic Esposito, chairman and chief executive of Antex Biologics in Gaithersburg. "Salmonella has been around a lot longer and gets a lot more attention, but you will be hearing more about Campylobacter than salmonella [in the future]." Potential Windfall Antex Biologics, a biopharmaceutical firm, is the only company in the world developing a vaccine for Campylobacter. The company is working with both the US Navy and pharmceutical giant SmithKline Beecham to develop a product that prevents Campylobacter related illness - which can cause severe diarrhea and in some cases death. If successful, analysts project the vaccine will be worth between $200 million and $400 million a year. Revenues like that would be enough to drive cash-poor Antex deep into profitability. "[Antex] has to show the reduction of bacteria levels and the translation of that effect into the reduction of diarrhea levels", said First Boston biotech analyst Shekbar Basu. "These are still early trials, but so far SmithKline Beecham is very positive about the outcomes Antex has had in animal testing." Four million Campylobacter infections occur in the United States each year, according to national health authorities. Worldwide, up to 500 million cases of Campylobacter-induced diarrhea are reported annually. Combined with pneumonia, the dehydration caused by severe diarrhea causes half of all deaths of children under age 5. "I think the incidence of Campylobacter infection as actually under-reported," Esposito said. "A lot of people who have upset stomachs or diarrhea don't go to the hospital". Campylobacter, he said, is usually spread through infected chicken meal. In the United States, studies suggest that 70% to 90% of chickens carry the pathogen. GROWING CHALLENGE Until recently, proper cooking and handling of chicken meal and the antibiotics given to the birds while alive, kept the bacteria in check. But it's not that easy anymore. "You are starting to find antibiotic-resistant strains of Campylobacter emerging," Esposito said. Additionally, scientists are beginning to suspect Guillain Barre Syndrome, an acute paralytic illness, may follow Campylobacter infections - about 5000 cases of Guillain Barre occur in the United States each year. Antex has several other vaccines in clinical trials, but the Campylobacter vaccineis farthest along in the pipeline. If all goes as planned, the company could be seeking approval on the patented product as early as 2000. There is mention of last years third quarter results and the Deloitte & Touche fastest growing companies list for this year. If you read this article carefully, you will have seen a big ANALYST talking about Antex. Albeit no hype .... but an analyst nonetheless. On another note ..... I am not sure how many of you have seen the investment banking model for Antex. Anyway .... the current valuation of Antex ...FULLY DILUTED (35 million shares) ..... was currently $2.51. THe interesting part is that my model used only $60 Million dollars in the calculation for Campylobacter. You can now see why I am very excited ....... if I plug in $200 million and Antex goes to Phase III trial soon ..... the valuation POPS TO $6.52 PER SHARE FULLY DILUTED !!!!!!!!!!!!!!!!!! ($10 current out) Oh geezzzz ...... I think I wet my pants !!!!! I think we are about to embark to new levels this year with Antex. I'm sure you all know what I have been doing the last two days ...... buying more Antex shares ! Comments ???? Mike