Faster more Reliable Than Emergency IV World's First Adult Intraosseous Infusion System Canadian and FDA Approval Received $250,000,000 Annual World Market Delivers Drugs and Fluids in 90 Seconds 5 Years Research & Development Marketing & Sales to Begin in 1997 International Civilian & Military Markets
COMPANY PROFILE
CORPORATE OBJECTIVE
PYNG's principal objective is to be the worldwide leader in the development and commercialisation of Adult Intraosseous Infusion Systems.
HISTORY
PYNG Technologies Corp. was incorporated in 1987 and became a reporting issuer through an initial public offering of its securities in May, 1988. At that time, the Company's principal business was a molded plastic extrusion line operated by a subsidiary, Canadian Custom Profiles Ltd. The subsidiary has produced a positive cash flow ($300k - $400k) for the past seven years.
Pyng Medical Corp. (The second subsidiary) was formed on December 2, 1992 as a B.C. based biomedical joint venture partnership to secure the Worldwide License Agreement of the Board of Regents of the University of California to the Intraosseous Infusion technology and relevant patents. This License was obtained on September 1,1993. Since then Pyng has received its own stand-alone patent for its unique technology and has developed the F.A.S.T.1TM, First Access for Shock and Trauma, the world's first adult intraosseous infusion system.
Pyng contracted with the British Columbia Institute of Technology (BCIT) under the Health Applied Research and Development program in 1993 to undertake engineering, scientific and medical aspects of the F.A.S.T.1TM commercialization plan. Two key personnel, Dr. David L. Johnson and Judy Findlay, have subsequently joined PYNG from BCIT to complete the development and commercialisation of the F.A.S.T.1TM system.
F.A.S.T.1 Intraosseous Infusion System
Lifesaving technology for emergency healthcare providers, F.A.S.T.1TM provides fast, effective intraosseous infusion with variable depth control. Developed by a team of scientific and medical professionals, F.A.S.T.1TM ensures safe, reliable operation in pre-hospital environments.
F.A.S.T.1TM can be used to provide drugs for medical emergency, or volume fluid resuscitation for treatment of haemorrhagic shock. Typical flow rates for normal saline are 30ml/min under gravity feed and 125ml/min with a pressurized bag or syringe-stopcock manual pump.
A 250ml bag of Hypertonic Saline Dextan (HSD), equivalent to nearly 2 litres of normal saline, can be infused using a syringe- stopcock pump in only 2.5 minutes.
THE PROBLEM
Major trauma and blood loss, cardiac arrest, dehydration, deep shock, and other medical emergencies necessitate rapid, reliable access to a patient's blood stream to administer drugs and fluids. In the pre-hospital emergency environment, an infusion line placed in an arm vein is the standard route for obtaining this access. Throughout the world each year, over a million attempts to place intravenous (IV) lines fail, 10% of all attempts. The average times taken to achieve IV access can be as little as 1.5 minutes but can range to more than 10 minutes.
Paramedics who attend civilian emergencies often work in confusing and disrupted physical settings. Military personnel face the additional chaos of armed conflict and unpredictable factors of time and distance in the pre-hospital environment. In both civilian and military emergencies, the patient's compromised status frequently defeats the caregiver's attempts to gain rapid intravenous access.
THE SOLUTION
Pyng Medical Corp. has addressed the need for a faster, more reliable vascular access route, usable in emergency environments. Pyng's solution is the F.A.S.T.1TM Intraosseous Infusion System. With the F.A.S.T. 1TM system, vascular access in adults can be reliably achieved in about one minute in pre-hospital emergency or battlefield conditions.
F.A.S.T.1TM can be used to provide drugs for medical emergency, or volume fluid resuscitation for treatment of haemorrhagic shock. Typical flow rates for normal saline are 30ml/min under gravity feed and 125ml/min with a pressurized bag or syringe-stopcock manual pump.
A 250ml bag of Hypertonic Saline Dextan (HSD), equivalent to nearly 2 litres of normal saline, can be infused using a syringe- stopcock pump in only 2.5 minutes.
Intraosseous infusion (IOI) is a proven medical technique for getting drugs and fluids into the bloodstream. Resuscitative drugs and volume replacement fluids quickly flow from the bone marrow through small blood vessels to enter the central venous system. The frequent difficulty of accessing veins in children and infants has made IOI a necessary alternative to IV access in emergency pediatric care. The F.A.S.T.1TM makes the procedure available to adult patients.
Pyng Technologies commitment to developing a successful intraosseous infusion system has resulted in the F.A.S.T.1TM System. The system has proven to be fast, effective, easy-to-use, and safe for use in the pre-hospital and hospital emergency environments.
KEY PERFORMANCE CHARACTERISTICS
Key performance characteristics of the F.A.S.T.1TM System are:
within about 70 seconds of initiating the procedure, fluid is flowing into the sternal marrow subcutaneous portal and low profile dome, and strain relief patch ensure immunity to external interference flow rates from about 30ml/min (gravity drip) to 125 ml/min (pressure cuff or syringe/stopcock pump), and 250 ml/min (single syringe) with a 250 ml bag of HSD, syrine/stopcock delivery of equivalent to nearly two litres of normal saline in 2.5 minutes can remain in place for up to 24 hours.
FAST
In evaluation trials with the F.A.S.T.1TM System, practicing paramedics have achieved vascular access in 60-90 seconds. In literature reports, paramedical and medical users have indicated that vascular access should be achieved in less than about 90 seconds. In contrast, a number of reported studies indicate that pre-hospital placement of IV typically takes about 90 seconds to 10 minutes and may take considerably longer.
EFFECTIVE
Intraosseous infusion, which is the basis of the F.A.S.T.1TM System, is an effective route for delivering resuscitative fluids to the patient's bloodstream. In addition, the installation of IOI overcomes a problem inherent in standard venous access in emergency situations - the difficulty of locating veins in a patient with severely compromised medical status.
EASY
The skills required to use the F.A.S.T.1TM match those of the intended user, and only minimal training is required to familiarize the caregiver with the easy-to-use components and the simple procedure.
SAFE
The F.A.S.T.1TM release mechanism safely positions the Infusion Tube at a controlled depth in the marrow. The F.A.S.T.1TM System is safe for caregivers to use. The powerful bone probe mechanisms in the Introducer automatically retracts into the handle as it releases the Infusion Tube.
DESIGNED FOR EMERGENCY ENVIRONMENTS
The F.A.S.T.1TM System is built to meet the demands of military and civilian emergency environments. Its components are designed to speed vascular access and enable effective patient care despite the difficulties of the emergency environment.
Please visit the Company's web site at: pyng.com
For further information please contact Mr. Michael W. Jacobs, President at: (604) 875-4526 |
