EMERYVILLE, Calif.--(BW HealthWire)--March 16, 1998--An explosion of productivity in biotechnology research and development will have a major impact on biotechnology and pharmaceutical companies as the next century approaches, a noted industry analyst predicted Sunday. ÿÿÿÿ Dr. David Crossen, Managing Director/Senior Health Care Analyst at NationsBanc Montgomery Securities, told the Fourth Informed Investors Bay Area Biotech Forum that dramatic increases in productivity will give "big pharma" (pharmaceutical companies) a "compelling story in terms of raising its internal productivity, which has been flat for a long period of time. ÿÿÿÿ "As R&D spending climbs, the new drug approval trend will go up, spending will go up and productivity of that spending will go through the roof. ÿÿÿÿ "Combinatorial chemistry is giving the (drug) industry a gigantic library of compounds ... millions of compounds as opposed to hundreds of thousands," Crossen said, "and genomics is giving the industry many, many more targets to focus on. ÿÿÿÿ "Also, high throughput screening is being developed very rapidly allowing companies to screen at a much higher rate using much lower quantities of re-agents at a much, much lower cost. As a result, this is going to be a high-powered engine allowing companies to churn out compounds at a steady rate." ÿÿÿÿ Rapid advances in biotech R&D will also spur more competition among biotech and big pharma companies, increase the likelihood of mergers in biopharma, and shorten lifespans for drugs as newer products replace existing ones. "This is inevitable and the trend is dramatic, particularly the way it has evolved in the last two years," he said. ÿÿÿÿ Crossen's address climaxed the morning-long Forum that also included full analyst-style presentations, including Q&A, from top executives, three CEOS and two CFOs, of five leading biotechs -- Geron Corp. (NASDAQ:GERN), Gilead Sciences (NASDAQ:GILD), Xoma Corp. (NASDAQ:XOMA), Myriad Genetics (NASDAQ:MYGN) and Shaman
Pharmaceuticals (NASDAQ:SHMN). ÿÿÿÿ Audio cassettes of the Forum, which includes Crossen's slide presentation, are available for $25 plus $3.95 shipping/handling or $18 for a single presentation. To order tapes, call 800/992-4683. Check out www.informedinvestors.com for more information. ÿÿÿÿ Crossen's wide-ranging talk hit on several aspects of biotech investing, including importance of timing, trial results for potential new drugs, risks imposed by short sellers and the importance of analysts' expectations. Interestingly, Crossen said, the way biotechs present their stories -- both the presentation and the presenters themselves -- are key elements in how analysts and investors perceive the likelihood of those companies to succeed. ÿÿÿÿ Crossen also profiled a portfolio of biotech companies he believes have potential upside later in 1998 and 1999. In most cases, he emphasized, investors are wise to wait for announcements that major milestones or test results have been achieved rather than invest prior to such announcements. "You can buy a stock now and take the chances, or buy it 10 points higher when the data is out and still make a lot of money ... there are ways to make money and balance your overall risk." ÿÿÿÿ For instance, Crossen told attendees Centocor (NASDAQ:CNTO) could benefit from its drug Avakine being launched later this year. Also, BioChem Pharma (NASDAQ:BCHE) would benefit if, as expected, its drug Lamivudine receives approval in China and Latin America. Favorable test results could help Cell Therapeutics (NASDAQ:CTIC) and strong product sales may drive PathoGenesis (NASDAQ:PGNS) stock higher, Crossen said. ÿÿÿÿ Other stocks that carry good upside, depending on successful trials, product launches or partnerships, include Biotime (NASDAQ:BTIM), Liposome (NASDAQ:LIPO), Sonus (NASDAQ:SNUS), Intercardia (NASDAQ:ITRC), Myriad Genetics, Transkaryotic Therapies (NASDAQ:TKTX), Dura Pharmaceuticals (NASDAQ:DURA) and Alteon (NASDAQ:ALTN). He discussed why he believes they have potential upside. ÿÿÿÿ Finally, don't be surprised, Crossen added, if biotech giant Amgen (NASDAQ:AMGN) makes an acquisition in 1998, potentially involving one of the companies listed above. "They've hired a big M and A (mergers and acquisitions) team and are very proactively looking at ideas," Crossen said. "Amgen's Neupogen could be helped a lot by having a broader cancer franchise ... " ÿÿÿÿ Since 1993, Sacramento-based Informed Investors has been linking investors with management of public companies. Informed Investors represents individual investors who collectively hold an estimated $1.5 billion in investable assets.
ÿÿÿÿ CONTACT: Informed Investors ÿÿÿÿÿÿÿÿÿÿÿÿÿ Bob Taylor/Steve Chanecka/Tim Quast, 916/448-8222 or ÿÿÿÿÿÿÿÿÿÿÿÿÿ 800/992-4683
ÿÿÿÿ KEYWORD: CALIFORNIA ÿÿÿÿ INDUSTRY KEYWORD: BANKING MEDICINE PHARMACEUTICAL BIOTECHNOLOGY
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