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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?

To: Flagrante Delictu who wrote (18437)	4/1/1998 12:43:00 PM
From: David L. Hachey	Respond to of 32384

Bernie, I might also add that a chronic rise in TG levels with time is a much more serious problem than an acute, short-term spike. In our protocol, if the chronic rise in TG levels exceeds 400 mg/dL, the dose is lowered or discontinued until it drops to a safe level. Retinoids are known to raise TG levels, but the mechanism is uncertain. My colleagues and I are still arguing about this issue. Can't say too much more because of NDA's (non-disclosure agreements <grin>). Regards, ...Dave