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Biotech / Medical : Eli Lilly -- Ignore unavailable to you. Want to Upgrade?

To: LoLoLoLita who wrote (131)	4/7/1998 6:18:00 PM
From: Anthony Wong	Respond to of 641

David and All, the DJ take on today's action, nothing you don't already know: April 07, 1998 4:47 PM DOW JONES ONLINE NEWS ELI LILLY SHARES CLIMB ON POSITIVE NEWS ABOUT BREAST CANCER DRUG NEW YORK -(Dow Jones)- Shares of Eli Lilly & Co. advanced 4.5% Tuesday after trial results showing Zeneca Group PLC's breast cancer treatment Tamoxifen may be effective in preventing breast cancer sparked speculation that a drug made by Eli Lilly might have similar results, analysts said. NYSE-listed shares of Eli Lilly (LLY) rose $2.75 to finish at $63.875 on volume of 9.8 million, compared with average daily volume of 3.9 million. Like Tamoxifen, Eli Lilly's Evista is a selective estrogen receptor modulator. Both products are thought to have roughly equivalent action on breast and bone cancers, analysts said. Monday, researchers said Tamoxifen reduces the incidence of breast cancer in high-risk women by 45%. Eli Lilly's Evista is currently available and indicated for the prevention of osteoporosis in postmenopausal women. -Jennifer Fron Mauer; 201-938-5287 Copyright (c) 1998 Dow Jones & Company, Inc. All Rights Reserved.

To: LoLoLoLita who wrote (131)	4/7/1998 6:28:00 PM
From: Anthony Wong	Read Replies (2) \| Respond to of 641

FOCUS - Tamoxifen data lifts Lilly, zaps Zeneca Tuesday April 7, 4:54 pm Eastern Time By Kevin Drawbaugh CHICAGO, April 7 (Reuters) - Strong data on the breast cancer-fighting value of a drug called tamoxifen on Tuesday surprisingly undercut the stock of the company that makes it and instead boosted the stock of a company that does not. In a seemingly paradoxical market response, shares in Zeneca Group Plc (ZEN - news) fell $6.25 to $141.25, while Eli Lilly & Co. (LLY - news) rose $3.25 to $64.375, both on the New York Stock Exchange in heavy trading. Analysts said the market response actually reflected somewhat rational expectations that were not surprising. The stock of Zeneca, the British drug maker, ran up sharply on Monday on news that a clinical trial with tamoxifen was halted early because it was so effective that researchers no longer wanted to withhold it from control group patients taking dummy pills. The National Cancer Institute study of 13,388 women at high risk of breast cancer showed the drug cut incidence of the disease by 45 percent in women taking the 35-year-old drug. Researchers said the results were the first to show that breast cancer can not only be treated, but prevented. However, investors took profits in Zeneca's stock on Tuesday as analysts pointed out that tamoxifen has already lost patent protection in Europe and will lose it in the United States in 2002, severely limiting the drug's potential as a big money-maker. ''The financial benefit to Zeneca is limited,'' said Hambrecht & Quist drug industry analyst Alex Zisson. Zeneca took in 1997 worldwide revenues of $508 million from the drug, about half of which came from the United States, where it is sold under the brand name Nolvadex. ''The clinical study was interesting, but I'm not sure it will stimulate an explosion of usage of the drug for prevention of breast cancer,'' Zisson said. Lilly's stock rose because the company makes the recently launched osteoporosis drug Evista, known generically as raloxifene, which is chemically similar to tamoxifen. Both are selective estrogen receptor modulators -- drugs that change the actions of estrogen in the female body. Analysts said the tamoxifen data supplied Lilly investors with a rationale that is tenuous, at best, for piling into a stock that has under-performed its pharmaceutical industry peers so far in 1998. ''We have a stock that's really lagged the group and people have been waiting to get in,'' said Jeffrey Chaffkin, drug industry analyst at PaineWebber. ''I'm not sure the tamoxifen data is a good reason to buy the stock. But people were looking for an excuse,'' he said. Analysts cautioned that data showing tamoxifen to be effective at preventing breast cancer may not apply to Evista, but added that Evista is seen as promising in combatting that disease and has many years of patent protection ahead of it. A Lilly spokesman said on Monday that the Indianapolis-based company expects data to be presented in mid-May at an American Society of Clinical Oncology meeting on Evista and breast cancer. Lilly's stock had been hurt recently by new prescription data for Evista, which has not hit the market as strongly as expected since its launch late last year, analysts said.

To: LoLoLoLita who wrote (131)	4/8/1998 12:09:00 AM
From: Hiram Walker	Read Replies (1) \| Respond to of 641

David, I don't have my material here,its at work. But Dong Quay, is a natural plant estrogen,and if you look to the Orient,and especially Japan,you will find that plant estrogens are used often to replace naturally produced estrogens. Well, I am a pharmacist,and see little need for a majority of the medicines in pharmacy. St. John's Wort,is a natural seratonin reuptake inhibitor,albiet milder than Prozac or Paxil. But it is prescribed at leat 7-1 for mild depression to Prozac in Germany. Echanecia is a natural macrophage and natural killer cell stimulant,and there is no other on the market. It was originally found by the indians of the midwest. Saw Palmetto,lestens prostate problems just as effectively as Hytrin or Proscar. Why do we need all these me too products at such a price? If the drug companies ever find a truely unique product,then put it on the market,other than that,I don't want more expensive medicines,without any benefit. I have been getting approximately 10-20 calls a day about Viagra,is there that many impotent males from the Boomer Generation? The data is not hard facts here,just from memory from recent readings. Hiram