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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?


To: Mudcat who wrote (19021)4/14/1998 9:32:00 AM
From: Henry Niman  Respond to of 32384
 
Mudcat, I really don't think that you understand what is and is not to be expected in the popular press articles. The NY Times article was in the "Science" section and was on Tamoxifen. As noted, even when the upcoming followup prevention trial pitting Tamoxifen against Evista was mentioned, there was no mention of LLY, Evista, or Raloxifene. The articles are NOT intended to present a list of compounds under development or companies developing them.

NO COMPANY was mentioned in the entire article, even though it was quite lengthy. NO COMPOUND was mentioned although many SERMs (Evista, Droloxifene, Idoxifene, CP-366,156, TSE424) being developed by several companies (LLY, PFE, AHP, SBH), and some other compounds (Targretin, Panretin) have chemopreventive properties and they synergize with Tamoxifen.

To expect Targretin, Panretin, or Ligand to be mentioned in such an article is extremely chavinistic, and not reality based.



To: Mudcat who wrote (19021)4/14/1998 9:47:00 AM
From: Henry Niman  Respond to of 32384
 
Here is another article from today's NY Times SCIENCE section. I does discuss Tamoxifen itself in more detail and does indicate that the new compound to be tested in the next NCI breast cancer prevention trial is Raloxifene.

However, there is no indication that Raloxifene (an APPROVED SERM for PREVENTING osteoporosis) is actually Evista and is sold by LLY (and presentations at the upcoming ASCO meeting will show that it PREVENTS BREAST CANCER).