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To: Grainne who wrote (21120)	4/29/1998 3:05:00 AM
From: LoLoLoLita	Respond to of 108807

Christine, I don't know about lufenuron in the form of a suspension, but it probably is administered by mouth as you say. For my 10.4-lb cat, the monthly lufenuron dose prescribed was 204.9 mg, in the form of a round tablet with a diameter of 10 mm. This is pretty big. Any bigger and it would be very difficult to administer. The cats in that study were continually reexposed to new fleas, simulating an indoor cat who is allowed to regularly go outside to be reinfected. Lufenuron does not kill adult fleas. Rather, if an adult flea feeds on blood from a treated cat, the eggs laid by that adult will not hatch. Perhaps lufenuron would be more effective if the experiment had simulated the adoption of a flea-ridden cat into a house with no fleas, but keeping the cat inside thereafter. Another thing to consider is that if the research was sponsored by the manufacturer of Advantage, that that might explain the 100% effectiveness of imidacloprid. Modern scientists need to be business persons, after all, or they don't eat. David P.S. At t=8 days after treatment with Program and Advantage, Tina appears to be completely free of fleas, and I am not aware of the presence of stray fleas in the house.