To: Jeffrey L. Henken who wrote (676 ) 5/5/1998 4:30:00 AM From: Aishwarya Respond to of 2887
Why are analyst's so bullish on the stent market ? Will the scope of this device increase exponentially ? Could it be that with the ease of use of these devices trigger huge sales: Check this report out from the health digest.Survey Says...Multiple Stenting Is Okay Paper: Early and Intermediate Term Clinical Outcome After Multiple Coronary Stenting Authors: Chauhan, A et al Source: Heart. 1998;79:29-33. Type: Clinical study Summary: Coronary stenting has become accepted as a means of improving the success rate of percutaneous transluminal coronary angioplasty (PTCA) and reducing the rate of restenosis, and as a treatment for failed angioplasty. However, the clinical outcome of patients who have had multiple coronary stents implanted has not be established. This study examined immediate and intermediate term clinical outcome in 140 patients who had undergone multiple coronary stent implantation over a two-year period at a single high-volume angioplasty center. Most of the patients had unstable coronary syndromes. Outcome was measured in terms of death, cerebrovascular accidents, myocardial infarction (MI), coronary artery bypass surgery (CABG), and repeat angioplasty (PTCA). The angiographic success rate was 100% and the clinical procedural success rate was 93%. The mean follow-up was 11.9 months. The mean number of stents per patient was 2.4, and the mean number of lesions treated per patient was 1.4. There were 4 in-hospital deaths, and 5 patients had an MI before being discharged from the hospital. All in-hospital deaths occurred in patients presenting with an acute MI and cardiogenic shock. Three patients had a late MI. One patient with stent thrombosis underwent emergency CABG, and 3 other patients had late CABG. Eight patients had a repeat PTCA. Eighty-three patients were asymptomatic at follow-up and 121 were free from major clinical events. The investigators concluded that multiple stenting can be performed with a high procedural success rate and good intermediate term outcome. "The improved outcome after multiple stenting when compared with that of other observational studies may reflect increased operator experience and improved stent deployment techniques," they wrote. "Multiple coronary stenting in the presence of acute MI and cardiogenic shock, however, is associated with high in-hospital mortality." They note that "replication of these results is needed before clear conclusions can be drawn." This is the type of information that the industry looks for in determining the efficay of the device. Hopefully we should start seeing ABMI stent trials commence. BTW: Great posts Jeff and all others who are taking time to post and keep it up. Go ABMI, regards, Sri.