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Biotech / Medical : Antex Biologics (ANTX) -- Ignore unavailable to you. Want to Upgrade?

To: Pilot who wrote (920)	5/22/1998 9:41:00 AM
From: Jake's mom	Respond to of 1476

Otitis media in children may be caused by viral or bacterial pathogens. Treatment with antibiotics remains controversial, actually, because "doing nothing" may clear the infection as quickly as antibiotics in some studies. Nevertheless, most pediatricians treat with antibiotics. Often, bacterial infections follow viral infections, presumably because the viral infection causes swelling of the eustacian tubes and poor drainage of the middle ear, leading to infection. Otitis media is more common in the winter, during "respiratory virus season." There are many other viruses that are associated with respitatory infection and otitis media (ie, RSV, parainfluenza, adenovirus, rhinovirus). Hence, wiping out influenza will only treat one of the many viruses. My understanding was that the Antex vaccine targets the most common bacterial pathogen (H. flu), which, if you believe bacteria are a problem, is probably more broadly applicable. On a cautionary note, the idea of a nasal spray that can be administered at home sounds like a great idea, but I dont think it will work. You would be amazed at how nearly impossible it is to universally get people to administer something correctly--many drugs that are available as sprays take "training" to give correctly. I would advocate clinics or some other way that trained individuals could administer the spray. Hope this helps Jake's mom (pediatric intensivist)