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To: Brett Fleischman who wrote (20774)5/22/1998 11:40:00 AM
From: cool  Respond to of 34592
 
ORVX--7 M float--some DD--

OraVax, Inc. Joins DynPort In Department of Defense
Contract To Develop FDA-Licensed Vaccines Against
Potential Biological Warfare Agents

CAMBRIDGE, Mass., May 04 /PRNewswire/ -- OraVax, Inc. (Nasdaq: ORVX - news)
announced today its participation in a defense contract awarded to DynPort L.L.C., as Prime
Systems Integration Contractor. The contract is for the Joint Vaccine Acquisition Program (JVAP)
of the U.S. Department of Defense (DoD). DynPort's proposal was chosen from four bids offered
to the Department of Defense's public Request for Proposals. OraVax is working with DynPort
and the JVAP office to refine plans for the advanced development and routine manufacture of
selected vaccines under this contract. Several vaccines are anticipated to be manufactured by
OraVax at its Canton, Massachusetts production facility.

The Joint Vaccine Acquisition Program is a $322 million, 10-year program for the development,
production, testing, FDA licensure and storage of vaccines to protect U.S. armed forces against
potential biological warfare agents. The JVAP is implemented by the DoD through the Joint
Program Office for Biological Defense, for which the U.S. Army is the lead agency. This program
was developed to ensure that the military will have access to a supply of FDA-approved vaccines
effective against potential biological warfare agents. The vaccines under the JVAP will be subject
to the same scrutiny and rigorous examination the FDA applies to vaccine products for civilian use.

''Recent current events show just how vital it is to be prepared to protect against the threat of
biologic warfare,'' said Lance K. Gordon, Ph.D., President and Chief Executive Officer of
OraVax. ''We are very pleased to have the opportunity to manufacture a series of vaccines that
are important for national defense. Once approved by the FDA, these products could also be
made more broadly available to counter the consequences of biologic warfare.''

Dr. Gordon also added, ''Performance under this contract should provide a long-term, stable
business unit to the Company that should extend our manufacturing operations and facilitate
OraVax's own proprietary product manufacture.''

DynPort, as prime contractor, and OraVax, as manufacturer for specified products, will receive the
existing investigational vaccines from the Department of Defense and will work with product
managers at the JVAP office to further establish the safety and efficacy required for licensure by
the FDA.

OraVax is a Cambridge, Massachusetts biopharmaceutical company engaged in the discovery and
development of innovative vaccines and antibody products to prevent or treat human infectious
diseases. The Company's largest program, Helicobacter pylori (H. pylori), is a joint venture with
Pasteur Merieux Connaught to develop vaccines against peptic ulcers and stomach cancer.
OraVax is also developing HNK20, a monoclonal IgA antibody nosedrop for prevention of infant
viral pneumonia caused by respiratory syncytial virus (RSV), and both a vaccine and a
stimulated-immune globulin for the prevention of colitis caused by Clostridium difficile, a common
complication of broad- spectrum antibiotic therapy. Additionally, the Company is developing the
ChimeriVax(TM) family of single-dose genetically-engineered vaccines based on the yellow fever
YF 17D vaccine strain virus. The first of these vaccines, targeting the Japanese encephalitis virus, is
currently in advanced preclinical development. Earlier stage research programs include vaccines
against dengue, tick borne encephalitis and hepatitis C viral infections.



To: Brett Fleischman who wrote (20774)5/22/1998 11:40:00 AM
From: Wayne Rumball  Read Replies (1) | Respond to of 34592
 
MIDL- It is not a question of whether the stuff works or not, it does. Question is will EXXON try to buy the stuff or the patent. MIDL will make money either way when their plant begins production. In any case the warrents are still in the money

There are 332 million gallons of gasoline sold daily in the U.S. Arcon
will receive 5.4 cents per gallon cash rebate from the federal government on all ethanol gasoline blended and sold by Arcon
containing DF-144.

A prominent international refining consultant retained by Arcon
has estimated the demand for DF-144 would be in excess of 70 plants to cover the northern and southern parts of California.
Until now, ethanol-based gasoline has not been sold in the state. Each DF-144 plant at 100,000 gallons per day will produce
$36 million per annum and net $7 million, and production commences in September 1998.

- DF-144 is not ether-based and is therefore more

environmentally ''friendly'' than additives such as MTBE or

ETBE.

A bill introduced by Senator Feinstein would require other states to drop MTBE from gasoline
(see MTBE on the Internet) and replace it with ethanol.