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To: Anthony Wong who wrote (218)6/5/1998 1:13:00 PM
From: Anthony Wong  Respond to of 1722
 
Merck Wins No Matter Outcome of Astra JV Restructure Talks
June 05, 1998 12:25 PM

By Jennifer Fron Mauer

NEW YORK (Dow Jones)--Merck & Co. (MRK) is
sitting in the catbird seat.

Whether or not the pharmaceutical giant ends its U.S.
joint venture with Sweden's Astra AB (A), analysts said,
Merck will benefit.

Earlier Friday both companies confirmed they are in
talks to restructure the 16-year-old venture, called Astra
Merck Inc., but neither would provide further details.

However, there are reports that to ensure its future
independence, Astra would be willing to give Merck
up-front cash payments and future royalties that could
total $10 billion.

"It sounds like they (Astra) are willing to give them
(Merck) so much money that they (Merck) will take it,"
said Alex Zisson, an analyst with Hambrecht & Quist.

While Merck doesn't necessarily need the additional
revenue, it wouldn't hurt. Analysts said the Whitehouse
Station, N.J., company could use the money to fund its
stock buyback program, to increase internal research
and development efforts and to acquire licensing
agreements for other companies' late-stage products.

Merck faces the loss in 2000 and 2001 of patent
protection for several blockbuster drugs - including
Pepcid, for treating ulcers, and Vasotec, for controlling
blood pressure - and could use a boost to its current
pipeline.

On the other hand, if the Astra Merck joint venture isn't
restructured, Astra Merck retains the "perpetual" right of
first refusal on U.S. rights to all new Astra drugs,
analysts said.

Though Astra's pipeline has been described as
"lackluster," past drugs have performed well, and there
is the hope that the future could be bright, too, analysts
said. Prilosec became a blockbuster antiulcer drug.
Losec, the ulcer treatment, has also been profitable. And
Friday Astra Merck received approval to market
Atacand for hypertension in the U.S. Atacand belongs
to an important new class of antihypertensive drugs that
is expected to become a leading class in the next
decade, Astra said.

NYSE-listed shares of Merck were up 3 3/8, or 2.9%,
to 119 1/16 on composite volume of 1.7 million shares,
compared with a daily average of 2.4 million.

Just two weeks ago, Merck agreed to sell its stake in
DuPont Merck Pharmaceutical Co. back to DuPont Co.
(DD) for $2.6 billion because the joint venture wasn't
contributing significantly to Merck's overall growth. But
analysts said the two moves are more likely a
coincidence of timing than the sign of a strategic change
in attitude.

"Merck has always been very aggressive in getting joint
ventures," Zisson added.

Indeed, the company has three others. Four years ago,
Merck forged a lucrative joint venture with French
vaccine maker Pasteur Merieux Connaught, a division of
Rhone-Poulenc SA. Last year, Merck created the
world's largest animal health and poultry-genetic
company, called Merial, with Rhone-Poulenc. And in
1989, it linked with Johnson & Johnson (JNJ) to form
Johnson & Johnson-Merck Consumer Pharmaceuticals
Co. to market over the counter products.

Hamant Shah, an independant analyst, said all three are
quite lucrative for Merck, and that the company is
unlikely to seek to end them any time soon.
-By Jennifer Fron Mauer; 201-938-5287;
jennifer-fron.mauer@cor.dowjones.com