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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: James Baker who wrote (3284)6/5/1998 11:26:00 PM
From: Brander  Read Replies (2) | Respond to of 9523
 
Off Topic:

Dr Baker, I am not disputing your data. However, on page 37 of The Medical Letter, Issue 1023, it says:

Staphylococcus aureus or epidermidis
non-penicillinase producing: Drug of First Choice PCN G or V
penicillinase-producing: a penicillinase-resistant Penicillin, such as cloxacillin or oxacillin.

In both cases, penicillins are the drugs of choice.

Clear things up?



To: James Baker who wrote (3284)6/6/1998 12:25:00 AM
From: Tunica Albuginea  Respond to of 9523
 
James Baker, you are absolutely correct.And that is what I was trying to explain to Brad; ie that MOST Staph Aureus isolated clinically ( 90%) IS resistant to PCN G. So that PCN G would NOT be your FIRST , empiric drug, in suspected staph infections as Brad contends. I wonder if he's got the point.

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Brad Anderson, I have no trouble with the Med Letter info that you posted just that you did not read the piece correctly and post complete information. Via personal message I was provided with a quote from the Med Letter and when you go and re-read it you will notice that it states for "NON-penicillinase producing S aureus" PCN is an appropriate first choice drug. The trouble is that 90% of clinical isolates of S auress ARE penicillinase PRODUCING. I don't need to go read the Med Letter to know this very basic microbiology.
James P. Baker, MD
Pediatric Infectious Diseases
aker,