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To: Anthony Wong who wrote (295)6/12/1998 12:52:00 AM
From: Anthony Wong  Read Replies (2) | Respond to of 1722
 
Merck, Monsanto Drugs May Show Promise in Cancer, Alzheimer's

Bloomberg News
June 11, 1998, 5:53 p.m. ET

Merck, Monsanto Drugs May Show Promise in Cancer, Alzheimer's

Washington, June 11 (Bloomberg) -- Monsanto Co. and Merck &
Co.'s developmental painkilling drugs, already shown to be potent
in treating arthritis, may also hold potential for staving off
life threatening diseases such as colon cancer and Alzheimer's,
according to an article in The New Yorker. Studies in mice have
shown Monsanto's so-called COX-2 drug Celebra's anti-inflammatory
effect suppresses the growth of polyps which are the first stage
of colon cancer; human trials have begun to see if the drug has
cancer prevention effects in people too, The New Yorker said. An
ongoing study of the brain benefit of a related group of pain
drugs called NSAIDS in Alzheimer's patients could point to an
even greater benefit with the super COX-2 painkillers, according
to Clifford Saper, a Harvard University neuroscience professor
quoted by the magazine.

The Merck and Monsanto drugs, the first of the COX-2 class
which work to suppress inflammation and pain without the stomach
and digestive side effects carried by traditional anti-
inflammatory drugs, are in the final stages of development and
could be on the U.S. market as early as 1999.
(The New Yorker 6/15 p. 32)

--Kristin Reed in Washington (202) 624-1858 /mfr