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Biotech / Medical : Repligen Corp (RGEN) -- Ignore unavailable to you. Want to Upgrade?


To: David Wise who wrote (79)7/23/1998 8:56:00 AM
From: E'Lane  Respond to of 395
 
Repligen Sues Bristol-Myers Squibb Over Immune-System Discovery

Boston, July 21 (Bloomberg) -- Repligen Corp. is suing Bristol-Myers Squibb Co. for not including the co-inventor of a method to regulate the body's immune system in a patent, and violating Repligen's rights to the discovery.

The suit filed against the world's largest cancer-drug maker in federal court in Boston Friday seeks unspecified damages and asks the court to declare Dr. Craig Thompson a co-inventor. Repligen claims Bristol-Myers misused trade secrets in not crediting Thompson, who licensed his rights to the invention to Repligen.

Thompson conceived of the idea of using a protein called CTLA4 to regulate the body's immune system and told his research colleagues at Bristol-Myers, the suit said. Bristol-Myers researched the idea, then won a patent covering the protein's use without mentioning Thompson's contribution, according to the court filing.

''Repligen was never able to form a partnership for clinical development of (the substance) with any one of a number of pharmaceutical companies which expressed interest in the technology,'' the company said in court papers.

New-York based Bristol-Myers also makes Clairol hair products and Excedrin painkiller. A company official had no immediate comment.

Needham, Massachusetts-based Repligen is developing treatments for cancer and eye diseases. Its primary focus is developing inhibitors of angiogenesis -- or new blood vessel growth -- to stop the growth of tumors.

Its shares rose 1/32 to 1 7/16. Bristol-Myers fell 5 7/8 to 119 15/16.

17:25:53 07/21/1998
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