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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: BigKNY3 who wrote (3533)6/15/1998 3:17:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 9523
 
(Dow Jones)Pfizer/Viagra : Aimed At Heading Off Competitors
June 15, 1998 2:53 PM

LONDON (Dow Jones)--Pfizer Inc. (PFE) said
Monday it's developing a new, improved version of
blockbuster oral impotence drug, Viagra - a move it
hopes will keep it one step ahead of potential
competitors.

Research now underway at the company's Sandwich,
U.K. laboratories is aimed at creating "Viagra with a
plus," according to Gill Samuels, director of science
policy for Pfizer Ltd., the U.K. unit of Pfizer Inc.

"Obviously we are aiming to stay on top," Samuels told
Dow Jones Newswires in an interview. "There is some
very promising stuff going on."

Apart from working on a female version of Viagra,
Samuels said, Pfizer also wants to reduce the drug's side
effects and make it faster acting. Viagra has been known
to cause headaches and can be dangerous if used by
people on heart medication. It also takes about an hour
for the drug to take effect.

Since being launched in April, Viagra has become one of
the biggest selling drugs in the world and captured more
than 90% of the U.S. market for impotence. But its
success has attracted the attention of competitors,
several of which are said to be developing their own
versions of the drug.

The biggest immediate threat to Viagra's dominance,
according to some, is Icos Corp.'s IC351, a product in
Phase II trials that is said to have similar efficacy to
Viagra but lack many of its side effects.

Pfizer Opens New U.K. Facility

Samuels said any improvements made to Viagra will still
require full clinical trials to prove safety and efficacy,
which could take some time.

"Viagra has only just come out," she said. "It's a very
very steep learning curve for us."

Samuels was among a group of staff and dignitaries
attending the official opening of an extension to Pfizer's
research and drug manufacturing operations in
Sandwich.

The new building was opened by U.S. ambassador
Philip Lader and Ken Moran, chairman and managing
director of Pfizer Ltd.

In an interview, Lader noted Pfizer's total investment in
the U.K. of around $1 billion is matched only by Ford
Motor Co. in terms of size.

"What the U.K. can offer is a well-educated, motivated
workforce, a regime that is very friendly to American
business practices and a highly sophisticated financial
community," he said.

Meanwhile, Moran said Pfizer is hoping to finalize by
July plans to further expand its U.K. research operations
at a cost of GBP241 million over the next three years.

Pfizer has said it will spend around $2 billion this year on
research.



To: BigKNY3 who wrote (3533)6/15/1998 5:29:00 PM
From: BigKNY3  Respond to of 9523
 
Just when you thought that the media would run out of Viagra themes.

BigKNY3

Wonder Drug Helped Me Woo Back Ex-Wife, Says Carrey

Comedy actor Jim Carrey says the love drug Viagra helped him woo back ex-wife Lauren Holly. Carey, 36, said his sex life was improved by the wonder pills.

The Sun quotes the funnyman telling a radio DJ: "I was working entirely too much. I was always too tired and I started to lose interest in sex. Then I heard about Viagra. It's incredible."

--------------------------------------------------------------------------------



To: BigKNY3 who wrote (3533)6/15/1998 5:44:00 PM
From: BigKNY3  Read Replies (4) | Respond to of 9523
 
Major article in this week's Newsweek.

BigKNY3

Around the world, approved or not, the little blue pill is a social phenomenon: the hottest new drug in history. Is this a good thing?
By Russell Watson

Rashid Gabdullin is only 32 years old, and he claims he's never had any complaints about his sexual performance. So when Gabdullin, a reporter for a Russian newspaper, tried the new anti-impotence drug Viagra, it was as a service to his readers. One dose did nothing for him, apart from inspiring "warm romantic feelings and a desire to meet a nice girl and take her to dinner," he wrote in the daily Komsomolskaya Pravda, which employs him as a correspondent in Central America. Only after he swallowed a double dose did the drug "work," he said. Gabdullin rushed out of his apartment, looking frantically for female company. Instead, he got stuck, alone, in a broken-down elevator. When he was set free, two hours later, the Viagra effect had faded away.
By now, Viagra is a global phenomenon. Introduced in the United States barely two months ago, the blue, diamond-shaped pill made by Pfizer Inc. is the hottest new drug in history almost everywhere in the world, including many countries where it's not yet legal for sale. Not since "sputnik" has a new word entered so many languages so quickly. In Mexico, humorists say Viagra means "the old lady is grateful," from the words vieja and agradecida. In Italy, enterprising marketers have come up with nonmedicinal "pizza Viagra" (topped with hot chili peppers), "gelati Viagra" (a blue ice cream that tastes like vanilla) and "formaggio Viagra" (a disappointingly soft cheese).
The news media are full of glowing, if unscientific, endorsements. Brazilian columnist Paulo Sant'Ana, a 58-year-old grandfather, took the pill on two occasions and described the results as "incessant, pleasurable" and so long-lasting that he stopped making love only when his partner begged for a rest. "Viagra won't let you down," he says. Former Italian soccer player Stefano Tacconi, 41, said the pill produced a duration of "twice as long as usual." But he said he wouldn't use the drug again because it takes the "poetry" out of sex.
In Jakarta, a Pfizer executive says he received a call from a man identifying himself as an official at Cendana, the residence of former Indonesian president Suharto. The caller asked for 100 Viagra tablets to be sent to the home of the 77-year-old ex-president. The Pfizer man told the caller Viagra was not yet approved in Indonesia and that the company had no supply on hand. He tactfully promised to do what he could. The next day, the Cendana official called back, telling the executive not to bother. "We've already got some in from the U.S.," he explained.
Currently, Viagra is legally available only in the United States, Brazil, Morocco and Mexico. It's coming soon to Colombia, South Africa and Thailand, and many other governments are rushing it through the approval process. Already there's a booming black market and a brisk traffic in counterfeit Viagra, some of which is nothing more than flour and cornstarch. There's also a gray market that uses telephone lines and the Internet to leap over national boundaries and legal technicalities. Computer users click onto Web sites like www.thepillbox.com, where Viagra is "this month's special." In Israel, a number obtained from a local newspaper ad reaches a telephone in Brooklyn, N.Y., where a man offers 10 pills for $280. The pills will be delivered anywhere in Israel within 24 hours, he says, and if a caller asks about the legality of the transaction, he growls: "Look, do you want it or not?"
Most callers do. Desperate, horny or merely curious, millions of men around the world are redrawing the romantic road map, hoping to find a pharmaceutical fountain of youth. The German tabloid Bild predicts that Viagra "can set off a sexual revolution, just like the anti-baby pill did 30 years ago." The implicit promise of Viagra--one not endorsed by its manufacturer--is good sex for all: old or young, gay or straight, male or female. "Henceforth the world will move for everyone," novelist Howard Jacobson writes in Britain's Evening Standard.
Maybe not. There are risks to buying Viagra, especially without a prescription and a medical exam. Pfizer says the drug is safe when used by the clinically impotent patients for whom it was intended. But all of the anecdotal evidence suggests that the current fad is more recreational than therapeutic, and for some, that could be fatal. So far, 16 deaths have been reported in the United States, among men 48 to 80. According to a report by the Food and Drug Administration, many of the victims had cardiovascular disease--making sex risky--and at least three were on nitroglycerin, a heart medicine that can be fatal when mixed with Viagra.
The blue pill is not an aphrodisiac. It increases the flow of blood to the genitals, causing or sustaining a male erection. But that's not a guarantee of great sex. "The magic bullet is no substitute for romance," says Dr. Leung Ying-kit, a sexologist who hosts a radio talk show in Hong Kong. "A poor lover plus Viagra does not make a good lover, but merely a poor lover with an erection." Some experts worry that Viagra will promote sex crimes. In Florida last week, an 89-year-old man was arrested for allegedly using a crowbar to club a 34-year-old woman who resisted his Viagra-fueled advances. "The whole thing is a big lie," he said.
Organized religion seems to be of two minds about Viagra: it can promote sin, or it can preserve marriages. The Vatican pharmacy says it doesn't sell the drug, but some Roman Catholic leaders cautiously endorse it. "If [Viagra] contributes to the healthy development of holy matrimony and is done with medical guidance, it is welcomed," Archbishop Roman Arrieta of Costa Rica said two weeks ago. "The Muslim clerics have blessed it, and the rabbis have blessed it," says Yaakov Katz, an official in Israel's Health Ministry. Although the drug probably won't be approved for sale in Israel for another two or three months, Rule 29C of the health code allows exceptions to be made on a "compassionate basis," says Katz. Since Viagra was introduced, Rule 29C cases have tripled in number. "Men in Israel are so stupid," says Orly Chen, who runs an impotence clinic in Jerusalem. "They don't even care if they die from it," she says, "as long as the sex is good."
In many countries, even legal Viagra sells for two or three times the U.S. price of $10 a pill. In some remote corners of Latin America, black-market prices as high as $175 a pill have been reported. In Germany, where the drug is not yet approved, supplies can be ordered from abroad at a cost of $500 for 30 pills. When customers hear the price--and learn that it isn't covered by health insurance--they usually lose interest, pharmacists report.
The global marketplace is flooded with cheaper alternatives. In Egypt, pharmacists sell a mixture of herbs, ginseng and royal jelly from beehives for only $10, calling it "Viagra for the poor." Third World markets offer a huge array of traditional sex-enhancers: powdered crocodile penis in Indonesia, lizard oil in India, an alleged Spanish-fly aphrodisiac for women in Mexico ("Slip it in her drink, she'll never know what hit her," says the packet). Then there are the counterfeits of Viagra; investigators have identified two producers in Europe and one in Lebanon's Bekaa Valley.
To give its customers a shot at the real thing, a travel agency in Japan offers Viagra Tours to Guam or Hawaii, where the drug can be purchased legally. A three-night trip to Hawaii costs $1,379, including a doctor's exam and two bottles of Viagra. So far, 25 Japanese men, mostly in their 50s, have taken the trip. Traffic is brisker across North American borders. Canadian men, who still can't buy the drug at home, are slipping across their southern frontier to shop for Viagra. "You could call it Vermont's No. 1 export," a urologist in Colchester told a reporter.
Although the sale of Viagra has been approved in Mexico, druggists in cities like Tijuana still cut corners. When a NEWSWEEK reporter visited more than two dozen pharmacies there last week, only five of them demanded the prescription required by law. "You need a prescription, but we don't make you show it to us," said one druggist. Pills made by Pfizer in Mexico were sold for $11.50 each; stronger pills made in the United States were available in some places, illegally, for $18 apiece.
Pharmacists say Viagra is more popular with foreign visitors than with Mexicans. "There is a pride factor among Mexican gentlemen who come to me for Viagra," says Dr. Eduardo Partida, a Tijuana physician. "They don't want to admit, many of them, that they have any sexual problems. Many of them tell me they are coming in for a friend or a relative." Viagra may not solve all of their sexual problems; lovemaking is more complicated than just achieving an erection. But on this Big Blue Planet, that's not a message that is likely to sink in with millions of eager Viagra men.
With Ron Moreau in Jakarta, Andrew Nagorski in Berlin, Mark Dennis in Jerusalem, Jamie Reno in Tijuana, Avani Mehta in New York and bureau reports

Newsweek 6/22/98 International/ Sex: The Globe Is Gaga for Viagra



To: BigKNY3 who wrote (3533)6/15/1998 7:04:00 PM
From: blankmind  Read Replies (1) | Respond to of 9523
 
- Thanks so much for the raw numbers and excellent analysis.

- As I've posted on the Vivus board, Viagra is definitely a runaway hit. But Vivus will be a good niche player in 40 or 50 countries - allowing it to make $2 a share.

- Thanks again for the excellent post & taking the time to put it all together. One of the best posts I've ever seen.



To: BigKNY3 who wrote (3533)6/16/1998 9:07:00 AM
From: utee  Read Replies (1) | Respond to of 9523
 
Do the script #'s you have posted include the large amount of product reaching Mexico,and other countries?

Utee