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Biotech / Medical : Agouron Pharmaceuticals (AGPH) -- Ignore unavailable to you. Want to Upgrade?

To: Bhag Karamchandani who wrote (4508)	6/17/1998 12:55:00 PM
From: tommysdad	Read Replies (2) \| Respond to of 6136

<<Can some one offer an empirical definition of " stabilized" ?>> They didn't get worse. I'm not being glib -- that's really what that means. SF asks what this data means -- good or bad. Essentially, a PI trial is a safety trial and any efficacy on the order of what they are reporting is not statistically significant and translation to PII/III is fairly random. So, if you're a glass-half-full kind of guy, it's "good", if you're a glass-half-empty kind of guy, it's "neutral". All this data means is that they can go forward to PII, which we already knew they had done. In a rational market, this news would have little impact.

To: Bhag Karamchandani who wrote (4508)	6/17/1998 11:40:00 PM
From: Bhag Karamchandani	Read Replies (2) \| Respond to of 6136

Re: AG3340; AGPH latest statement begs the question: What happened to the majority (close to 75 % 0f the patients (47 in total)) who were not included in the "stabilized" category?? Was period of treatment with AG3340 a factor?? Also are there any early indications of how AG3340 works with non- advanced ( again how does AGPH or anyone define advanced ) cancers? Is the glass one-third full and two thirds empty or vice versa???? I found the press release quite ambiguous. Hope it was not deliberate. Is the reference to second generation MMP a way to play down expectations re AG 3340? Very much hope we do not have another Thymatiq unfolding. Why not simply publish the statistical data summary????