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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?


To: Pseudo Biologist who wrote (22989)7/9/1998 5:15:00 PM
From: WTDEC  Respond to of 32384
 
PB, thanks for the information. We have all been patiently waiting for that. No need to be sorry.

Regards,

Walter



To: Pseudo Biologist who wrote (22989)7/9/1998 5:22:00 PM
From: celeryroot.com  Respond to of 32384
 
thx PB

Fugazi I thought you were camped out for us



To: Pseudo Biologist who wrote (22989)7/9/1998 8:58:00 PM
From: Henry Niman  Respond to of 32384
 
Here's the News of the Week summary from Science:

DRUG DEVELOPMENT:
Small Molecule Fills Hormone's Shoes

Marcia Barinaga

Drug companies have long sought small compounds that mimic the effects of protein drugs yet
evade breakdown in the digestive tract, but the small chemicals, which might be just 1/50 of a protein's size, seemed too puny to
turn on the proteins' surface receptors. Now, on page 257, researchers report their discovery of a small molecule that activates the
receptor for granulocyte-colony-stimulating factor, a cytokine that is commonly used to boost patients' immune systems after
chemotherapy. Although the new compound works in mice but not humans, it is being heralded as evidence that the right small
molecule can indeed fill a protein hormone's shoes.



To: Pseudo Biologist who wrote (22989)7/9/1998 9:29:00 PM
From: Henry Niman  Respond to of 32384
 
Bloomberg expects the news to move LGND's price tomorrow:

Ligand Pharmaceuticals Inc. (LGND): Researchers from the
drug company and SmithKline Beecham Plc (SB LN) said they've made
a discovery that could one day lead to a pill form of an immune-
system boosting drug that currently must be injected.
Ligand fell 5/16 to 12 7/16.