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To: NeuroInvestment who wrote (1026)7/17/1998 10:16:00 AM
From: Ariella  Read Replies (2) | Respond to of 1491
 
Dear NeuroInvestment:

Am I correct in assuming that the change to 200 mg. from 300 mg. dosage level for the third cohort of Phase II is good? I read it as they believe they have enough good news from first two groups and don't want to take any unnecessary chances with third portion of trial. The idea, after all, is to get into Phase III.

But why the note that they might increase number of sites? Are they concerned that the study has too few patients to make real statistical validity? Or just making sure every "i" is dotted, every "t" crossed?

Regards,
Ariella