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Biotech / Medical : Ionis Pharmaceuticals (IONS) -- Ignore unavailable to you. Want to Upgrade?


To: Adrian Wu who wrote (2176)7/30/1998 2:41:00 AM
From: SnowShredder  Respond to of 4676
 
Adrian,

Many oligoplexes enter the cells via receptor mediated endocytosis (ISIP's I do not know). Although many undergo some degree of degradation before escaping the endosome...decreasing transgene expression. Thus I'm curious to know if there is a special feature to aid disruption of the endosomal compartment, in turn increasing the efficiency.

Best of Luck,

Where'd He Go?