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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: Bluegreen who wrote (6845)7/30/1998 7:12:00 AM
From: Robert K.  Respond to of 17367
 
IF >if< bpi21 works, then would you prefer surgery or bpi21?............>
>Surgical treatment of extensive skin necrosis secondary to purpura fulminans in a patient with meningococcal sepsis.

Arevalo JM, Lorente JA, Fonseca R
Servicio de Cirugia Plastica y Unidad de Grandes Quemados, Hospital Universitario de Getafe, Madrid, Spain.
[Medline record in process]

Meningococcal sepsis is associated with a high mortality rate. These patients may show severe disseminated intravascular coagulation (DIC) and skin necrosis. There is very little published experience regarding the surgical treatment of this complication. The similarity between skin necrosis secondary to DIC and full thickness cutaneouos burns provides the rationale for its treatment as if it was a deep burn. We report the surgical treatment of extensive skin necrosis in a patient with meningococcal sepsis and DIC. This treatment is similar to that used in full thickness burns, including excision of necrotic tissue and coverage with autografts, as well as amputation of extremities if distal coverage is not possible.