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Biotech / Medical : Zonagen (zona) - good buy? -- Ignore unavailable to you. Want to Upgrade?

To: Bradpalm1 who wrote (5234)	8/15/1998 7:57:00 PM
From: George Acton	Respond to of 7041

\| Viagra's problem IS specifically with nitrates and nitrates are NOT \| in most high blood pressure medicines. This is accurate, as are all your postings I've seen. I've seen the Pfizer mailing concerning the danger of combiming nitrates with Viagra, and it is restricted to ONLY that class of drugs. And nitrates (nitrite in the case of the inhalant amyl nitrite) aren't in any preparations for high blood pressure. They relax smooth muscle, and preferentially the smooth muscle in the walls of coronary arteries, so they're for chest pain called "angina pectoris (sp?)" which results from insufficient blood flow to heart muscle. Many patients take nitrates, but only as needed for angina, so the patients are very aware of what they're taking, and why. --George Acton

To: Bradpalm1 who wrote (5234)	8/18/1998 12:36:00 AM
From: mchip	Read Replies (1) \| Respond to of 7041

<<This statement is factually incorrect. Viagra's problem IS specifically with nitrates and nitrates are NOT in most high blood pressure medicines.>> Thanks for clearing that up Brad. I'm glad I did not state it as fact! I'm not a medical doctor. don't even play one on TV <g>. <<Another factor . overlooked is the patient exclusion criteria they used>> Brad is there a resource to lookup study results and/or NDA filings? That kind of information seems quite useful. Also is there anyplace to find details of the payment schedule from SGP? The 5Mil accelerated payment made last qtr look much better than if they had not received it. My understanding is word about acceptance of the NDA should be decided mid-September. Is there another payment due then?