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Biotech / Medical : Agouron Pharmaceuticals (AGPH) -- Ignore unavailable to you. Want to Upgrade?


To: Captain Jack who wrote (5278)9/9/1998 4:15:00 PM
From: Steve Fancy  Read Replies (1) | Respond to of 6136
 
Top Stories: Rumors Push Agouron
Higher

By Jesse Eisinger
Senior Writer
9/9/98 2:33 PM ET

Shares of Agouron (AGPH:Nasdaq) were rising sharply
this afternoon on takeover rumors.

The name investors are hearing is DuPont (DD:NYSE),
which is trying to build a presence in biotechnology.

An Agouron spokeswoman said the company didn't
comment on rumors. A DuPont spokeswoman said the
same thing and added that DuPont has said it wouldn't
make a "large, dilutive acquisition" in expanding its
life-sciences business.

Investors in recent weeks have also latched onto Roche,
the Swiss drug company, as a possible acquirer. Biotech
analysts have dismissed that possibility because late last
year Roche walked away from a cancer drug partnership
with Agouron.

Agouron shares were up 2 1/16 at midafternoon to 28 on
heavy volume. Agouron stock has been weak since last
year around this time, down almost 50% from its high of 55
1/2. This year it's down about 5%, which looks pretty good
compared with the 23% drop in the Amex Biotech Index.

But takeover rumors are always tricky. The last refuge of
worried bulls is to float rumors about a takeover. There have
been relatively few takeovers in the history of biotech, as
bigger companies have preferred to cherry-pick good
products.

In this case, however, some analysts say it's not outlandish
to think that AGPH would be taken out. Charles Engelberg
of Americal Securities said he lifted his sell rating on
Agouron in early August after he decided a takeover wasn't
implausible.

Agouron sells Viracept, the leading protease inhibitor for
the treatment of AIDS. The drug brought in worldwide sales
of $409 million for fiscal 1998 ended in June, including $358
million in the U.S. The company forecasts U.S. sales of
$430 million to $440 million in fiscal 1999.

But some investors are concerned that the drug's sales are
not growing, and many short-sellers think sales of the
product will in fact shrink as competing AIDS treatments
and side effects eat into use of protease inhibitors.

An Agouron deal might make a good fit for DuPont. The
Wilmington, Del., chemicals giant filed for approval in June
for approval of Sustiva, another AIDS drug in the
nonnucleoside reverse transciptor family, raising the
possibility it might want to build an AIDS franchise. DuPont
gained rights to Sustiva this summer when it closed its
purchase of Merck's (MRK:NYSE) stake in their
pharmaceutical-development joint venture. Agouron, which
has licensed several other AIDS drugs, has ongoing cancer
research, but investors have not been overly impressed with
the quality of the company's science.

Agouron's Viracept and other earlier stage drugs will be
featured at a large antiviral conference, the Interscience
Conference on Anti-Microbial Agents and
Chemotherapy, to be held in San Diego at the end of the
month, which could be goosing the stock as well.

Agouron also has a heavy short position and it's possible
that some short-sellers are covering Wednesday.

Agouron's options were acting like traders were expecting a
sharp move upwards. Options traders typically focus on at-
and out-of-the-money calls to play takeovers, and those
were the busiest today. The September 25 calls, for
instance, traded 100 contracts and rose 2 ($200) to 3 1/2
($350) per contract in early action today.

Most of the options action took place in the October series,
possibly reflecting the belief that a deal, while expected in
some quarters, isn't imminent. The October 25 calls traded
138 contracts and the October 30 calls' volume reached
168, outstripping current open interest. The price jumps on
the contracts were also dramatic, as the October 130 rose
1 ($100) to 1 11/16 ($168.75), showing mounting interest in
the biotech's shares at 30.



To: Captain Jack who wrote (5278)9/9/1998 6:52:00 PM
From: Intel Trader  Respond to of 6136
 
re upside, for you longs, I hope so John. The recent events of our slightly wounded bull market don't have me hoping for much more than that AGPH may pull back to its recent low area where I may become interested again. The run over the last couple of days to 29 was rather phenomenal.

Careful on the s/l on overnight holds. They work fine during the day, if a stock isn't halted, but I'm sure you know that ; )

I may be wrong here, but as I see it, we will have continuing weakness in the markets until the presidential leadership issue is resolved. Such weakness can pull Agouron down below the recent lows where it could remain. However it eventually concludes, it needs to be relatively quick (ie clear Clinton of all wrong doing [highly unlikely] or resignation), otherwise things could turn very ugly over the next few months (impeachment).

Best regards,

it