To: DavidCG who wrote (3999 ) 9/17/1998 8:25:00 PM From: R>G> Read Replies (2) | Respond to of 5402
Hello DavidCG Reference about possible buyout Size of blood substitute market. While there are many factors that make it hard to determine the exact size of the market, I've tried to compile what I have found. Talking with Dr. Drees I asked what he thought the size of the market is. He said that world wide there are about 60 million transfusions a year. Each transfusion averages 2 pints. 60 million transfusions times 2 (2 pints /transfusion) equals 120 million pints. According to the World Health Organization (WHO), if there were not the shortage of donors, refrigeration problems, typing and cross matching, availability of testing equipment, etc. there could be 120-180 million transfusions per year. If you take an average of 150 million transfusions times 2 (2 pints /transfusion) you get 300 million pints. If you take either figure, multiply it by $300.00 which is what Dr. Drees and Sanguine feel is the price they would sell it at. In the first case 120 million pints times $300.00 is 36 billion per year In the 2nd case 300 million pints times $300.00 is 90 billion per year. Keep in mind the WHO is using figures that are above what is currently being used. Then you have to figure what percentage the competition is going to get,using outdated blood, even if they could solve the 75 year problem of acute toxicity, outdated blood accounts for only 2% of blood collected. (From page 6 Sanguine business plan) See previous posted message below. One of the big questions is how much of the market share will SGNC have. At this point in time 10% in the first 5 years. Dr. Drees said that they have a patent with the new surfactants already to go but that you want to do that at the last minute because then everyone can see what you are doing by reading the patent. He did say that because they have been at this so many years that their patent will cover everything so extensively that it will take until the patent runs out before the competition can come into the market which would be 10 years. If someone was able to find some angle around their patents he still estimated that they would have at least a 7 year jump on any competition. The fact is that this product has already undergone 20 years of testing and will only need a fraction of that amount. Again, this product has been in development from 1978. At that time, full product development cost co's 100+mill. Dr. Drees and Batelle have estimated 95-98% success on pher-02. FDA approval (since this will be approval on a 2nd generation improved product will be easier than the first time it was approved. (Courtesy of Chief Brody) I feel that taking into account the above information, also figuring that not everyone would want to use the new product, figuring that the outdated market is only 2%,the remaining market is very large. Plenty of room for more than 1 company. If Sanguine gets 10% of the market they will be a multi billion dollar company. I believe that if the animal efficacy tests show promising results that about 1/2 the way thru (tests should take 6-9 months) some larger company will either buy them out or do a joint venture. I believe that the synthetic blood will be the largest drug market ever. It all hinges on how the animal efficacy tests and human safety testing goes. As this is a 2nd generation drug verses a 1st generation drug, as Dr. Drees is the only one that I know who has already taken a blood substitute (While President or CEO of Alpha) and received FDA approval, I feel comfortable these things will come to pass. R>G>