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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: Anthony Wong who wrote (5591)9/18/1998 12:26:00 AM
From: Anthony Wong  Read Replies (1) | Respond to of 9523
 
Bloomberg:Pfizer's Viagra Linked to Patient's Heart Attack, Lancet Says

Bloomberg News
September 17, 1998, 7:01 p.m. ET

London, Sept. 17 (Bloomberg) -- A man with no prior history
of cardiac problems had a heart attack after taking Pfizer
Inc.'s blockbuster impotence drug Viagra, the latest in a series
of reports to raise concern about the drug's side effects.

Researchers said there was a suggestion of a link between
taking Viagra and heart attack in the case of a man, aged 65 and
with no record of high blood pressure, diabetes or heart
disease. Within 30 minutes of taking the drug the man suffered
acute chest pain.

''The close temporal relation between ingesting sildenafil
(Viagra) and the onset of severe chest pain due to acute
myocardial infarction ... suggests hat sildenafil was causally
related'' to the heart troubles, doctors said in a report to
British medical journal The Lancet.

The report comes as safety concerns about Viagra are
mounting. In the U.S. 69 patients who took the drug between
March and July later died. Pfizer and the U.S. Food and Drug
Administration maintain Viagra is safe when used properly.

The novelty of The Lancet's findings, though they concern
only one patient, stems from the man's lack of previous heart
troubles. Doctors and the company itself have warned of the
potential for heart problems in patients taking heart
medications that can have dangerous interactions with Viagra.

For example, in most of the 69 deaths reported by the FDA
in the U.S., where the drug has been sold since April, patients
were found to have at least one risk factor for heart disease.
That's why the FDA has said it hasn't found Viagra to be the
direct cause of death.

Viagra has seen unprecedented demand and garnered sales of
more than $400 million in its first three months on the market.
The company has recently faced several lawsuits from men who
claimed they suffered heart attacks after taking the drug,

The drug was approved for sale in the 15-nation European
Union earlier this week.

While the Viagra label doesn't contain a specific warning
for heart patients, it does advise doctors that sexual activity
carries risks, and ''physicians may wish to consider the
cardiovascular status of their patients before prescribing the
drug.''

--Marthe Fourcade in the London newsroom (44171) 330-7171 with