To: marc ultra who wrote (2288 ) 9/29/1998 6:05:00 PM From: jackie Read Replies (1) | Respond to of 4676
To: marc ultra From: jackie Tuesday, Sep 29 1998 7:22AM EST -Preview- marc, Absolutely correct. This is a wonderful story to have come out on ISIS. Some of the comments of scientists questioning the mechanism of our latest drug may throw some people off. But this is just science. It's a bunch of people discussing natural phenomena and trying to determine what is going on. There should be unending questioning of any model in science, including our drugs. However, that does not remove all of the other evidence pointing to the effectiveness of this science. The successful completion of these trials should put an end to some of the speculation regarding the real mechanism at work here. I was on vacation for three weeks and had the opportunity to read "The Making Of The Atomic Bomb" by Richard Rhodes. This is a wonderful read and I strongly urge anyone who wants to understand the fundamental 'messiness' of science. We are presented with the final product, models of physical events, in school. Our first impression might be these were received in their current, well developed, form. Nothing could be further from the truth. Smart people, like Bohr, Einstein, John von Neumann, barked up a lot of wrong trees before the current model of the atom was assembled. This book brings out the substance of the debates leading up to the nuclear model we have and what people knew, or thought they knew, down through the years. The same thing is going on with antisense. It's an idea that will be debated to its eventual fate, success or failure. Anyway, the article was terrific. Thanks for telling us about it. Jack Simmons