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To: one_less who wrote (9626)10/15/1998 2:56:00 PM
From: one_less  Respond to of 67261
 
Here Kitty, Kitty, Kitty

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PRO/AH> Inflammatory bowel disease, feline to human? - USA

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To: promed-ahead@usa.healthnet.org
Subject: PRO/AH> Inflammatory bowel disease, feline to human? - USA
From: Michael M Phillips <barmike@erols.com>
Date: Sat, 9 Nov 1996 18:59:59 -0500
Reply-To: promed@usa.healthnet.org
Sender: owner-promed-ahead@usa.healthnet.org

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INFLAMMATORY BOWEL DISEASE, FELINE TO HUMAN? - USA
==================================================

Date: Sat, 9 Nov 1996 17:52:40 -0500 (EST)
From: Michael M Phillips <barmike@erols.com>

I am a gastroenterologist practicing in Washington DC, and have seen a woman
without prior history of bowel disease develop idiopathic IBD shortly after
her house cat was diagnosed as having IBD. The cat's illness was
characterized by vomiting (which the patient cleaned up, without wearing
gloves etc).

The cat was gastroscoped by the veterinarian, and biopsies of the
stomach and duodenum revealed intense infiltration of lymphocytes and
monocytes. No cultures were done on the cat but he has responded to
predinsone.

The human developed bloody diarrhea shortly after the cat's
illness began. Cultures for enteric pathogens, ova and parasites and _C.
difficile_ toxin were negative. The patients was treated with Cipro 500mg BID
but failed to improve. A sigmoidoscopy revealed findings suggestive of IBD,
and biopsies revealed crypt abscesses and intense infiltration of
lymphocytes and monocytes. Flagyl 250 mg QID failed to improve the symptoms,
and corticosteroids have been started. The pathology appears to be similar
[to the cat's] which certainly suggests that an infectious agent could be the
cause of the [the illness of both the] cat and his owner.

Anyone deal with similar situations or have ideas as to the etiology?

--
Michael M Phillips, MD
<barmike@erols.com>

................................................................jw

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