To: stellerstar who wrote (542 ) 10/18/1998 8:17:00 PM From: Urlman Read Replies (1) | Respond to of 1255
REPOST FROM DAVIDCG: Cortex is indeed human testing its drug. In three ongoing studies. This is off CORX's latest SEC report: >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> AMPALEX (CX516) is currently being investigated in Phase I/IIa clinical trials at the National Institutes of Health (NIH) in Bethesda, in patients with Alzheimer's disease and patients with schizophrenia. An additional study in patients with schizophrenia is being conducted at the Erich Lindemann Mental Health Center in Boston. These trials follow three European studies that demonstrated that AMPALEX is safe and well tolerated on acute oral administration to healthy human volunteers. >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> also: <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< 'Operating results for fiscal 1998 reflect ongoing clinical testing of AMPALEX(R) (CX516) in patients with Alzheimer's disease and those suffering from schizophrenia,'' said Vincent F. Simmon, Ph.D., President and Chief Executive Officer. ''As we reported earlier, we are pleased with the safety profile experienced to date in these double-blind trials. In addition, although the number of patients analyzed to date is too small to draw statistical conclusions, preliminary results suggest that CX516 improves performance on several tests of memory and cognition in patients with schizophrenia.'' <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< What is interesting is that CORX just patented a compound which is 50 - 100 times stronger than what they are using in human testing currently! >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Cortex has completed a preliminary human safety study with a second generation AMPAKINE, CX691. This compound was designed to have a longer half life in humans, and the preliminary study has confirmed that it does. Furthermore, in a number of animal behavior assay systems, CX691 appears to be 50 to 100 times more potent than CX516 and has an impressive margin of safety. >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> What I like is that the National Institute of Health (national govt. operated) is testing CORX's drug...Talk about credibility. CORX also expects a strategic partner by year's end... whether or not that will occur, I don't know. To get more info, just read through CORX's SEC filing... Good Trading! -DavidCG