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Biotech / Medical : Agouron Pharmaceuticals (AGPH) -- Ignore unavailable to you. Want to Upgrade?


To: Steve Fancy who wrote (5523)10/19/1998 2:37:00 PM
From: Steve Fancy  Read Replies (1) | Respond to of 6136
 
Weekly scrip data for week ending 10/9...

New 4088 -1.4%
Refills 7510 -3.5%
Total 11,598 -2.8%

Monthly scrip data for September...

New 19,043 +5.2% unadj
Refills 33,357 +4.8% unadj
Total 52400 +5% unadj

Comments suggest holding at 32% market share and they remain ahead of competitors in total PI sales.

sf



To: Steve Fancy who wrote (5523)10/19/1998 2:39:00 PM
From: Steve Fancy  Read Replies (1) | Respond to of 6136
 
The comments last week came from Ms Wong. She apparently stated that a competitor is feeling AGPH may miss their numbers...not sure who the competitor was. My broker had filled in the blank with RS, but admitted today that he didn't know.

Elise apparently went on to say that she is confident they will hit her estimate of .21.

sf



To: Steve Fancy who wrote (5523)10/19/1998 4:55:00 PM
From: Bradpalm1  Read Replies (1) | Respond to of 6136
 
I've heard very positive rumors about AGPH's MMP inhibitor AG3340 in early Phase II/III trials for metastatic non-small lung cancer. With the recent elite status conferred upon anything 'anti-angiogenesis', perhaps word is filtering down to the street. These studies bear close monitoring.

Bradpalm1



To: Steve Fancy who wrote (5523)10/19/1998 5:07:00 PM
From: Steve Fancy  Respond to of 6136
 
Another version of the IMNR news...

Immune Response, Agouron To Work Together On HIV Treatment

Dow Jones Online News, Monday, October 19, 1998 at 16:57

CARLSBAD, Calif. -(Dow Jones)- Immune Response Corp. said Monday
Agouron Pharmaceuticals Inc. agreed to collaborate on the development
and sale of Remune, an experimental HIV treatment that aims to boost
patients' immune systems to fight the virus.
Immune Response, a biopharmaceutical company, said it may receive as
much as $77 million over the next two years, and the two companies will
share all Remune profits on a 50/50 basis.
Agouron is known for making Viracept, a protease inhibitor taken as
part of a so-called "drug cocktail." The drug combinations have been
cited with revolutionizing AIDS treatment because they can drive HIV in
the bloodstream down to nearly undetectable levels.
Remune is an experimental vaccine. It contains only proteins inside
the core of HIV, and not its outer envelope. Scientists think that with
virus levels reduced significantly by treatment with the combination
drug therapy, the immune system can create so-called helper cells once
it sees the HIV proteins contained in Remune.
Immune Response (IMNR) received an initial $3 million research and
development payment and $2 million for the purchase of 126,758
unregistered common shares. The shares were purchased at a premium, the
company said.
Immune Response said Agouron (AGPH) is expected to make a series of
quarterly research and development payments and to purchase unregistered
common shares.
Immune Response will manufacture Remune's commercial supply. Agouron
will have exclusive rights to market the treatment in North America,
Europe and other countries, after receipt of regulatory approvals.
Copyright (c) 1998 Dow Jones & Company, Inc.
All Rights Reserved.



To: Steve Fancy who wrote (5523)10/19/1998 5:32:00 PM
From: Steve Fancy  Respond to of 6136
 
So, lets see, based on "...$2 million for the purchase of 126,758 unregistered common shares..." AGPH paid approximately $15.78 a share. Any comments? Anyone know if AGPH could have backed out up till today, or, can they back out of future committments?

Options activity today seems to lean towards the bullish end of the scale with 970 Nov calls traded at strikes between 25-45 and 578 Nov puts at 30 and 35 strikes.

sf