To: Steve Fancy who wrote (5523 ) 10/19/1998 5:07:00 PM From: Steve Fancy Respond to of 6136
Another version of the IMNR news... Immune Response, Agouron To Work Together On HIV Treatment Dow Jones Online News, Monday, October 19, 1998 at 16:57 CARLSBAD, Calif. -(Dow Jones)- Immune Response Corp. said Monday Agouron Pharmaceuticals Inc. agreed to collaborate on the development and sale of Remune, an experimental HIV treatment that aims to boost patients' immune systems to fight the virus. Immune Response, a biopharmaceutical company, said it may receive as much as $77 million over the next two years, and the two companies will share all Remune profits on a 50/50 basis. Agouron is known for making Viracept, a protease inhibitor taken as part of a so-called "drug cocktail." The drug combinations have been cited with revolutionizing AIDS treatment because they can drive HIV in the bloodstream down to nearly undetectable levels. Remune is an experimental vaccine. It contains only proteins inside the core of HIV, and not its outer envelope. Scientists think that with virus levels reduced significantly by treatment with the combination drug therapy, the immune system can create so-called helper cells once it sees the HIV proteins contained in Remune. Immune Response (IMNR) received an initial $3 million research and development payment and $2 million for the purchase of 126,758 unregistered common shares. The shares were purchased at a premium, the company said. Immune Response said Agouron (AGPH) is expected to make a series of quarterly research and development payments and to purchase unregistered common shares. Immune Response will manufacture Remune's commercial supply. Agouron will have exclusive rights to market the treatment in North America, Europe and other countries, after receipt of regulatory approvals. Copyright (c) 1998 Dow Jones & Company, Inc. All Rights Reserved.