SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Microcap & Penny Stocks : Pharmos(PARS) -- Ignore unavailable to you. Want to Upgrade?


To: yosi s who wrote (1461)10/24/1998 2:40:00 PM
From: Ariella  Read Replies (1) | Respond to of 1491
 
All you doctors put your thinking caps on:
sciweb.com

Describes patent granted to PHarmos in May for a part of the business we usually don't speak about.
_______________________

Patent Number 5750142
Issue Date 1998 05 12
Assignee Pharmos Corp
Investors Friendman, Doron; Aldouby,Yanir

Title Dry compositions for preparing submicron emulsions

Abstract The present invention relates to dry, stable compositions
which can be reconstituted to form pharmaceutical or
cosmetic emulsions, and to methods for making such
compositions. An emulsion is formed from about 0.2 to 25
weight percent of a first component of an oil, about 0.1 to
5 weight percent of a second component of an emulsifier,
about 0.25 to 25 weight percent of a cryoprotectant of an
amino compound, such as one or more amino acids, peptides or
protein hydrolysates, and an aqueous component, wherein the
amino compound is present in an amount that is equal to or
greater than that of the first component. Optionally, a
co-emulsifier, a suspension agent, a preservative, an
antioxidant and a drug can be added to these emulsions.
Thereafter, the emulsion is lyophilized to form dry
compositions that have from about 40 to about 90 weight
percent of the amino compound; from about 0.1 to about 20
weight percent of the emulsifier; and from about 0.2 to
about 40 weight percent of the oily component. By combining
the dry composition with an appropriate quantity of an
aqueous liquid, the composition is reformed as an
oil-in-water emulsion.

Exmp. Claim 1
Ex Claim text A lyophilized composition comprising:
from about 0.2 to about 40 weight percent of an oil;
from about 40 to about 90 weight percent of a
cryoprotectant, wherein said cryoprotectant comprises an
amino compound and is present in an amount that is equal to
or greater than the amount of said oil; and
from about 0.1 to about 20 weight percent of an emulsifier;
the components being present in combination such that, when
combined with an appropriate quantity of an aqueous liquid,
the composition forms an oil-in-water emulsion; wherein the
amino compound is selected from the group consisting of a
straight amino acid, a branched amino acid, a nontoxic salt
of a straight amino acid, a nontoxic salt of a branched
amino acid, an ester of a straight amino acid, an ester of a
branched amino acid, a peptide, and a protein hydrolysate.