To: John F. Dowd who wrote (6204 ) 11/4/1998 5:42:00 PM From: Anthony Wong Respond to of 9523
John, one or more of the following may have contributed to today's weakness: 1) The PFE/Hoechst news (which is good news to me), excerpt from Bloomberg article:news.com Shares of Germany's Hoechst rose 1.94 deutsche marks to 72.35 marks. Pfizer, which will now have to share the market with Hoechst's drug unit Hoechst Marion Roussel, fell 3 5/16 to 105 15/16. San Carlos, California-based Inhale rose 1 7/8 to 30 7/8. Inhaled insulin could generate as much as $1 billion in annual sales, said Caroline Copithorne, an analyst at Prudential Securities. ''It's going to expand insulin into a much larger market because of the higher price and the conversion of some patients, who are now reluctant to use injections, to inhaled insulin,'' she said. Until the Frankfurt factory is complete, Hoechst will provide the bulk insulin to Inhale for conversion into powered form. The Hoechst insulin will be used for final clinical trials, slated to begin in the first half of 1999, and initial sales of the product, the companies said. The addition of Hoechst's insulin production and its commitment to the new manufacturing site was critical for New York-based Pfizer and Inhale Therapeutics, since neither has much experience in the tricky process of making insulin and the inhaled, powder formulation is requires massive amounts of bulk insulin. Now, it's clear there will be a large enough insulin supply, and a strong international sales staff, to support a very successful product, Copithorne said. 3) Dura Pharmaceutical has some bad news from the FDA about their inhale technology (re. their inhaled asthma drug) and is down big today. 2) Henry Niman's post at the MTC board said that Merck had filed for Vioxx approval at FDATo: jopawa (445 ) From: Henry Niman Wednesday, Nov 4 1998 11:44AM ET Reply #446 of 465 Bear Stearns has a rumor that MRK has already filed a Vioxx application, but the report came out earlier. Details in New Therapeutics section of biocognizance.com 3) PFE has reached a Peabody peak of $110 today