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To: NASDBULL who wrote (13282)11/19/1998 11:52:00 AM
From: DavidCG  Respond to of 119973
 
CompuMed OsteoGram(R) Gets Highest Osteoporosis Prediction Score of
Any Bone Density Test Ever in Major Clinical Study

Company Press Release

SOURCE: CompuMed, Inc.

CompuMed OsteoGram(R) Gets Highest Osteoporosis Prediction Score of
Any Bone Density Test Ever in Major Clinical Study

Results of 3-Year U.S. Study Show OsteoGram Test Dramatically Outperforms Direct
Testing of the Spine, Ultrasound, and
Competing Hand and Wrist Measurements for Predicting Those Most Likely to Suffer
from Osteoporosis

MANHATTAN BEACH, Calif., Nov. 18 /PRNewswire/ -- CompuMed, Inc.
(Nasdaq: CMPD - news) announced today the results of a landmark 3-year
prospective study conducted by scientists from the Hawaii Osteoporosis Foundation,
Merck & Co., Inc. (NYSE: MRK - news) and CompuMed under grants
from Merck and the U.S. Public Health Service. The findings are published in the latest
issue of the highly respected journal Calcified Tissue International.
CompuMed's OsteoGram bone density measurements were found to dramatically
outperform every other test for identifying those most likely to go on to suffer
spinal fractures caused by osteoporosis.

The OsteoGram predicted the incidence of future spine fractures with a relative risk of
3.4. Each 10% decrease in bone density as measured by the OsteoGram led
to a 3.4 fold (340% greater) increased risk of incurring spine fractures during the course
of the study. This is the highest relative risk for predicting spine fractures
ever demonstrated by any bone mass measurement technique in a major prospective
clinical study. Direct bone density measurements of the spine utilizing
expensive, whole body dual-energy x-ray scanners yielded only a 1.9 relative risk for
predicting future spine fractures, while competing hand and wrist measurement
techniques and heel ultrasound were the least predictive measurements, with relative
risks of 1.7, 1.8 and 1.5 respectively.

''The medical community should be very excited about the CompuMed technology,''
said Michael A. Davis, M.D., Ph.D., Professor of Radiology and Director of
Radiologic Research at the University of Massachusetts Medical Center. ''Whole body
bone scanners can occupy entire exam rooms, cost more than $100,000,
take up to 30 minutes to perform a single procedure, and give you less than a 2.0
relative risk for spine fracture prediction. On the other hand, CompuMed
technology achieves a 3.4 relative risk, which is dramatically better, and can be
integrated into compact, relatively inexpensive units that can perform patient-friendly
tests in less than 2 minutes. This is clearly a breakthrough technology.''

The loss of height often seen in people as they age is the result of spinal fractures and
collapse caused by osteoporosis and degenerative arthritis. By identifying
those most at risk, physicians can provide patients with appropriate therapy that can
prevent spinal and other types of osteoporotic fractures, such as hip fractures.
Over 28 million Americans currently suffer from osteoporosis, which causes over 1.5
million spine fractures and over 250,000 hip fractures each year.

CompuMed is harnessing the power of its bone density testing technology in its new
Automated OsteoGram® 2000 and Digital OsteoView® 2000, affordable
desktop devices designed to meet the needs of the hundreds of thousands of physicians
worldwide who have patients at risk for osteoporosis. CompuMed plans to
submit a 510(k) marketing clearance application for the Automated OsteoGram® 2000
to the U.S. Food and Drug Administration within the next few weeks.

CompuMed, based in Manhattan Beach, California, develops solutions to important
medical problems through the use of computer technology. In addition to the
OsteoGram and OsteoView, CompuMed has developed computer-aided telemedicine
services for cardiology and currently provides on-line computer
interpretation of electrocardiograms (ECGs) to physicians, government and corporate
healthcare providers.