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Biotech / Medical : Texas Biotech (TXB) -- Ignore unavailable to you. Want to Upgrade?

To: Dauntless who wrote (738)	11/25/1998 10:15:00 AM
From: Bill Tomko	Read Replies (1) \| Respond to of 834

I completely agree with your anal. However, I'm deeply troubled by mgt. and do have questions re thier competance to achieve the potenial. I don't mean to keep beating a dead horse but I failure to get the product approved last may was just inexcusable. Christ sake it has been given to over 100,000 patients in Japan! This problem combined with the more important problem IMO of very poor information flow makes me VERY uncomfortable with mgt. and unsure about the future.

To: Dauntless who wrote (738)	2/6/1999 11:59:00 PM
From: Cacaito	Read Replies (2) \| Respond to of 834

News from Roche, Refludan (Novastan competitor in the HiT market) 10,000 patients in a prospective study with placebo control (not historical controls) completed and shown effective for unstable angina to decrease infarcts/mortality. Plus side: Novastan once approved for HiT, could be used off label for angina and/or stroke increasing the possibilities beyond the tiny HIT market. Negative side: A proven drug like Refludan with strong data will give more problems for Novastan already rejected data. A new study will be of long duration and expensive (either for HIT or stroke or angina). The FDA will not have a rush for approving a Refludan similar since the need is fulfill. There are many more drugs in angina, yes they are not cheaper but they are proven effective. Not many effective drugs in Stroke, maybe they should go after this indication from the start but they try to shortcut via HIT. So far the strategy is not paying.